Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2008, Vol. 6 ›› Issue (8): 806-809.doi: 10.3736/jcim20080807

Special Issue: Acupuncture & Moxibustion

• Original Clinical Research • Previous Articles     Next Articles

Therapeutic effects of scalp-acupuncture in patients with vascular dementia induced by cerebral infarction: a randomized controlled trial

Yi-cheng Liu1(), Hong-xing Zhang2, Guo-hua Chen3, Wen-li Wu4, Jing-jing Hu2, Wen-jun Wan5, Chao-yang Ma5   

  1. 1. Department of Radiology, Integration of Traditional and Western Medicine Hospital of Wuhan, Wuhan, Hubei Province 430022, China
    2. Department of Acupuncture, Integration of Traditional and Western Medicine Hospital of Wuhan, Wuhan, Hubei Province 430022, China
    3. Department of Neurology, Integration of Traditional and Western Medicine Hospital of Wuhan, Wuhan, Hubei Province 430022, China
    4. College Office, Integration of Traditional and Western Medicine Hospital of Wuhan, Wuhan, Hubei Province 430022, China
    5. Department of Rehabilitation Medicine, Central Hospital of Wuhan, Wuhan, Hubei Province 430014, China
  • Received:2007-12-26 Online:2008-08-20 Published:2008-08-15

Objective: To investigate the effects of scalp-acupuncture on intelligence in patients with vascular dementia (VaD).
Methods: A total of 108 VaD patients were randomly divided into two groups: scalp-acupuncture group and Western medicine group. The scores of Mini-Mental State Examination (MMSE), Blesse Dementia Scale (BDS), Hasegawa Dementia Scale (HDS), Ability of Daily Life (ADL) before and after treatment in the two groups were detected.
Results: A total of 92 patients completed the treatment. The scores of MMSE, BDS and HDS in the two groups were significantly increased, and the ADL scores significantly declined (P<0.05). There was no difference in the scores of MMSE, BDS, HDS and ADL between the two groups before and after the treatment. There was no difference in the total effectiveness between the two groups (P>0.05).
Conclusion: Scalp-acupuncture therapy could improve the clinical intelligence level of VaD patients.

Key words: dementia, vascular, scalp acupuncture, intelligence, randomized controlled trials

CLC Number: 

  • R491.32

Table 1

Baseline data in two groups"

Group n Sex (male/female) Average age (x±s, year) Severity
Mild Moderate Serious
Western medicine 45 29/16 66±1 22 21 2
Scalp-acupuncture 47 30/17 65±1 23 21 3

Table 2

MMSE, BDS, HDS and ADL scores in two groups before and after treatment (x±s)"

Group n HDS ADL BDS MMSE
Western medicine
Pre-treatment 45 10.12±5.05 58.85±25.36 16.44±4.31 18.36±2.47
Post-treatment 45 18.56±6.13* 33.59±23.26* 22.24±4.56* 23.35±3.49*
Scalp-acupuncture
Pre-treatment 47 10.06±4.96 57.74±24.22 16.07±4.49 18.06±2.52
Post-treatment 47 18.45±5.42* 32.36±20.68* 22.15±4.51* 23.06±4.63*

Table 3

Clinical effects in two groups after treatment[Cases (%)]"

Group n Obvious effect Improvement Failure Deterioration
Western medicine
30-day treatment 45 8 (17.77) 29 (64.44) 6 (13.33) 2 (4.44)
One month after treatment 45 8 (17.77) 30 (66.67) 5 (11.11) 2 (4.44)
Two months after treatment 45 8 (17.77) 30 (66.67) 5 (11.11 ) 2 (4.44)
Scalp-acupuncture
30-day treatment 47 8 (17.02) 30 (63.83) 7 (14.89) 2 (4.26)
One month after treatment 47 9 (19.15) 30 (63.83) 6 (12.77) 2 (4.26)
Two months after treatment 47 9 (19.15) 29 (61.70) 7 (14.89) 2 (4.26)
[1] American Psychiatric Association. Diagnostic and statistical manual of mental disorders(4th ed)[M]. Washington: American Psychiatric Press, 1994,( 4th ed):147-154
[2] Hachinski VC, Lassen NA, Marshall J . Multi-infarct dementia. A cause of mental deterioration in the elderly[J]. Lancet, 1974,2(7874):207-210
[3] Liang YD . Revised Hasegawa dementia scale[J]. Riben Yi Xue Jie Shao, 1992,13(9):420
梁亦邓 . 用于痴呆诊断的修订长谷川量表[J]. 日本医学介绍, 1992,13(9):420
[4] McKhann G, Drachman D, Folstein M , et al. Clinical diagnosis of Alzheimer's disease: Report of the NNCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease[J]. Neurology, 1984,34(7):939-944
doi: 10.1212/WNL.34.7.939
[5] China Association of Acupucture-Moxibustion. China scalp-point programme of the international standardization. The First National Academic Conference of Scalp Acupuncture. 1984. Chinese.
中国针灸学会. 中国头皮针穴名国际标准化方案. 全国首届头针学术会议资料. 1984.
[6] Ministry of Health of the People's Republic of China. Guidelines of clinical research on Chinese new herbal medicine, draft criteria for guidelines of clinical research on Chinese new herbal medicine treatment of senile dementia. 2000. Chinese.
中华人民共和国卫生部. 中药新药临床研究指导原则·中药新药治疗老年期痴呆的临床研究指导原则(草案). 2000.
[7] Mo FZ, Liu SH, Li JQ , et al. A comparative study of therapeutic effects between laser acupoint irradiation and acupuncture on symptoms in patients with vascular dementia[J]. Xian Dai Kang Fu, 2001,5(3):36-37
莫飞智, 刘颂豪, 李建强 , 等. 激光穴位照射与针刺对血管性痴呆症状的疗效对照研究[J]. 现代康复, 2001,5(3):36-37
[8] Liu YC, Luo MJ . A comparative analysis of MR imaging of vascular dementia caused by cerebral infarct: before and after a combined treatment using acupuncture and medications[J]. Zhongguo Yi Liao Qi Xie Xin Xi, 2006,12(9):7-14
刘翼程, 骆明军 . 脑梗死所致痴呆患者针药结合治疗前后MRI的对比分析[J]. 中国医疗器械信息, 2006,12(9):7-14
[9] Bao YH, Feng WM, Zhu GX , et al. Observation on clinical therapeutic effect of long-time retaining needles at scalp-acupoints on vascular dementia[J]. Zhongguo Zhen Jiu, 2004,24(2):81-84
包烨华, 冯伟民, 朱国祥 , 等. 头穴久留针治疗血管性痴呆的随机对照研究[J]. 中国针灸, 2004,24(2):81-84
[10] Guo LL, Yan MH, Zhang BH . Effect of nimodipine on congnitive function of vascular dementia patients[J]. Zhongguo Kang Fu, 2006,21(4):272
doi: 10.3870/j.issn.1001-2001.2006.04.031
郭莉莉, 闫明华, 张保虹 . 尼莫地平对血管性痴呆患者认知功能的影响[J]. 中国康复, 2006,21(4):272
doi: 10.3870/j.issn.1001-2001.2006.04.031
[11] Liu YC, Zhang HX, Wan WJ , et al. Progress of acupuncturein in treatment of vascular dementia[J]. Zhongguo Kang Fu Yi Xue Za Zhi, 2007,22(3):274-275
doi: 10.3969/j.issn.1001-1242.2007.03.031
刘翼程, 张红星, 万文俊 , 等. 针刺治疗血管性痴呆的临床研究进展[J]. 中国康复医学杂志, 2007,22(3):274-275
doi: 10.3969/j.issn.1001-1242.2007.03.031
[1] Dastan M. Khoshnaw, Abhijit A. Ghadge. Yoga as a complementary therapy for metabolic syndrome: A narrative review. Journal of Integrative Medicine, 2021, 19(1): 6-12.
[2] Brody Slostad, Tejinder Khalsa, Kathleen Young, Hildalicia Guerra, Anjali Bhagra. A case-based approach to integrative medicine for cardiovascular disease prevention. Journal of Integrative Medicine, 2020, 18(2): 159-162.
[3] Noriko Shinjyo, James Parkinson, Jimmy Bell, Tatsuro Katsuno, Annie Bligh. Berberine for prevention of dementia associated with diabetes and its comorbidities: A systematic review. Journal of Integrative Medicine, 2020, 18(2): 125-151.
[4] Chun-song Hu, Tengiz Tkebuchava. SEEDi1.0-3.0 strategies for major noncommunicable diseases in China. Journal of Integrative Medicine, 2017, 15(4): 265-269.
[5] Chen Fu, Nevin Lianwen Zhang, Bao-xin Chen, Zhou Rong Chen, Xiang Lan Jin, Rong-juan Guo, Zhi-gang Chen, Yun-ling Zhang. Identification and classification of traditional Chinese medicine syndrome types among senior patients with vascular mild cognitive impairment using latent tree analysis. Journal of Integrative Medicine, 2017, 15(3): 186-200.
[6] Maria T.Chao, AlexandraChang, SanjayReddy, James D.Harrison, JosephAcquah, MiriaToveg, TrilceSantana, Frederick M.Hecht. Adjunctive acupuncture for pain and symptom management in the inpatient setting: Protocol for a pilot hybrid effectiveness-implementation study. Journal of Integrative Medicine, 2016, 14(3): 228-238.
[7] Nouran A. Aleyeidi, Khaled S. Aseri, Shadia M. Matbouli, Albaraa A. Sulaiamani, Sumayyah A. Kobeisy. Effects of wet-cupping on blood pressure in hypertensive patients: A randomized controlled trial. Journal of Integrative Medicine, 2015, 13(6): 391-399.
[8] Meng-yue Liu, Cheng-wei Wang, Zhou-peng Wu, Ning Li. Electroacupuncture for the prevention of postoperative gastrointestinal dysfunction in patients undergoing vascular surgery under general anesthesia: Study protocol for a prospective practical randomized controlled trial. Journal of Integrative Medicine, 2014, 12(6): 512-519.
[9] Zhong-liang Liu, Wei-rong Zhu, Wen-chao Zhou, Hai-feng Ying, Lan Zheng, Yuan-biao Guo, Jing-xian Chen, Xiao-heng Shen. Traditional Chinese medicinal herbs combined with epidermal growth factor receptor tyrosine kinase inhibitor for advanced non-small cell lung cancer: A systematic review and meta-analysis. Journal of Integrative Medicine, 2014, 12(4): 346-358.
[10] Zhi-yi Zhou, Ling Xu, He-gen Li, Jian-hui Tian, Li-jing Jiao, Sheng-fu You, Zhi-fen Han, Yi Jiang, Hui-ru Guo​, Hui Liu​. Chemotherapy in conjunction with traditional Chinese medicine for survival of elderly patients with advanced non-small-cell lung cancer: Protocol for a randomized double-blind controlled trial. Journal of Integrative Medicine, 2014, 12(3): 175-181.
[11] Jian Liu, Chuan-bing Huang, Yuan Wang, Gui-qin Xu, Yuan-yuan Cheng, Yun-xia Feng, Lei Liu, Ya-jun Qi. Chinese herbal medicine Xinfeng Capsule in treatment of rheumatoid arthritis: Study protocol of a multicenter randomized controlled trial. Journal of Chinese Integrative Medicine, 2013, 11(6): 428-434.
[12] Tian-zhan Wang, Yu Chen, Yan-ming He, Xiao-dong Fu, Wang Yi, Yan-qiu Xu, Hong-jie Yang, Hong-li Xue, Yi Liu, Xiao-tao Feng, Teng Zhang, Wen-jian Wang. Effects of Chinese herbal medicine Yiqi Huaju Qingli Formula in metabolic syndrome patients with microalbuminuria: a randomized placebo-controlled trial. Journal of Chinese Integrative Medicine, 2013, 11(3): 175-183.
[13] Chung-wah Cheng, Shu-fei Fu, Qing-hui Zhou, Tai-xiang Wu, Hong-cai Shang, Xu-dong Tang, Zhi-shun Liu, Jia Liu, Zhi-xiu Lin, Lixing Lao, Ai-ping Lü, Bo-li Zhang, Bao-yan Liu, Zhao-xiang Bian. Extending the CONSORT Statement to moxibustion. Journal of Chinese Integrative Medicine, 2013, 11(1): 54-63.
[14] Stephen D. Anton, Kacey Heekin, Carrah Simkins, Andres Acosta. Differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health. Journal of Chinese Integrative Medicine, 2013, 11(1): 2-10.
[15] Hong Wang , Jing-tian Ou , Xin Zhao , Ying Guoz , Hao-ping Mao. Vasodilator effect of oroxylin A on thoracic aorta isolated from rats. Journal of Chinese Integrative Medicine, 2012, 10(8): 880-885.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Jin-zhou Tian, Jing Shi, Xin-qing Zhang, Qi Bi, Xin Ma, Zhi-liang Wang, Xiao-bin Li, Shu-li Shen, Lin Li, Zhen-yun Wu, Li-yan Fang, Xiao-dong Zhao, Ying-chun Miao, Peng-wen Wang, Ying Ren, Jun-xiang Yin, Yong-yan Wang, Beijing United Study Group on MCI of the Capital Foundation of Medical Developments. An explanation on "guiding principles of clinical research on mild cognitive impairment (protocol)". Journal of Chinese Integrative Medicine, 2008, 6(1): 15-21
[2] Yi-ting He, Qing-lin Zha, Jian-ping Yu, Yong Tan, Cheng Lu, Ai-ping Lv. Principal factor analysis of symptoms of rheumatoid arthritis and their correlations with efficacy of traditional Chinese medicine and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 32-36
[3] Jun Cai, Hua Wang, Sheng Zhou, Bin Wu, Hua-rong Song, Zheng-rong Xuan. Effect of Sijunzi Decoction and enteral nutrition on T-cell subsets and nutritional status in patients with gastric cancer after operation: A randomized controlled trial. Journal of Chinese Integrative Medicine, 2008, 6(1): 37-40
[4] Wei Zhang, Xiang-feng Lu, Xiao-mei Zhang, Jian-jun Wu, Liang-duo Jiang. A rat model of pulmonary fibrosis induced by infusing bleomycin quickly through tracheal intubation. Journal of Chinese Integrative Medicine, 2008, 6(1): 60-67
[5] A-gao Zhou, Yong Zhang, Gang Kui, De-Yun Kong, Hai-liang Ge, Qiu-hua Ren, Jia-rong Dong, Sheng Hong, Xu-ming Mao, Yin Wang, Hui-zheng Zhang, Shu-jun Wang. Influence of traditional Chinese compound recipes with different efficacy on body weight, tumor weight and immune function in H22 cancer-bearing mice. Journal of Chinese Integrative Medicine, 2008, 6(1): 77-82
[6] Guo-hong Yuan, Xiao-jing Pang, He-chao Ma. Synergic effects of Danggui Buxue Decoction in reducing toxicity of cytoxan in tumor-bearing mice. Journal of Chinese Integrative Medicine, 2008, 6(1): 83-88
[7] Li Zhou, Hong-xing Zhang, Ling-guang Liu, Wen-jun Wan. Effect of electro-acupuncture at Fenglong (GV 16) on nitric oxide and endothelin in rats with hyperlipidemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 89-92
[8] Jin-zhou Tian, Jing Shi, Xin-qing Zhang, Qi Bi, Xin Ma, Zhi-liang Wang, Xiao-bin Li, Shu-li Shen, Lin Li, Zhen-yun Wu, Li-yan Fang, Xiao-dong Zhao, Ying-chun Miao, Peng-wen Wang, Ying Ren, Jun-xiang Yin, Yong-yan Wang, Beijing United Study Group on MCI of the Capital Foundation of Medical Developments. Guiding principles of clinical research on mild cognitive impairment (protocol). Journal of Chinese Integrative Medicine, 2008, 6(1): 9-14
[9] Xin-jun Wang, Ling-ling Wang . A mechanism of endogenous opioid peptides for rapid onset of acupuncture effect in treatment of depression. Journal of Chinese Integrative Medicine, 2010, 8(11): 1014-1017
[10] Bo Wang , Wei Yan , Li-hui Hou, Xiao-ke Wu. Disorder of Tiangui (kidney essence) and reproductive dysfunction in patients with polycystic ovary syndrome. Journal of Chinese Integrative Medicine, 2010, 8(11): 1018-1022