Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2011, Vol. 9 ›› Issue (12): 1326-1332.doi: 10.3736/jcim20111208

Special Issue: Traditional Chinese Medicine

• Original Chinical Research • Previous Articles     Next Articles

A study of diagnostic criteria for traditional Chinese medicine syndromes in osteoporosis

Li Dong-tao1(),Li Fu-yu1,Wang Jian1,Liu Ji-hong1,Yan Nan1,Cheng Yong-mei1,Hu Ai-hua2,Jiang Hong-yang3,Shi Feng-lei4,Zhang Mei-zeng5,Li Jie6,Wei Ling-bo6,Jiang Rong-qin7   

  1. 1. Department of Traditional Chinese Medicine, Qingdao First Sanatorium, Jinan Military Region, Qingdao 266071, Shandong Province, China
    2. Qingdao Social Welfare Institution, Qingdao 266071, Shandong Province, China
    3. Department of Orthopedics, Center Hospital of Haiyang, Haiyang 265100, Shandong Province, China
    4. Second Department of Orthopedics, Qingdao Orthopaedic and Traumatology Hospital, Qingdao 266021, Shandong Province, China
    5. Department of Neurology, the Affiliated Hospital of Medical College Qingdao University, Qiangdao 266071, Shandong Province, China
    6. Department of Traditional Chinese Cardiology, Qingdao Haici Medical Group, Qingdao 266033, Shandong Province, China
    7. Department of Medical Services, Qingdao Hospital of Integrated Traditional Chinese and Western Medicine, Qingdao 266002, Shandong Province, China
  • Received:2011-06-23 Accepted:2011-08-12 Online:2011-12-20 Published:2018-08-17

Objective: To establish diagnostic criteria for common traditional Chinese medicine (TCM) syndromes in osteoporosis.
Methods: Based on the collection and analysis of related medical literature, clinical investigation, and expert discussion, a draft of preliminary diagnostic criteria for the basic syndromes of TCM in patients with osteoporosis was formulated. Then it was used in clinic for verification and revised repeatedly until a formal version of diagnostic criteria was satisfactorily achieved.
Results: The basic syndromes listed in the diagnostic criteria for patients with osteoporosis consisted of two parts: qualitative diagnosis and localization diagnosis. Results of qualitative diagnosis showed that the qualitative syndromes included damage of essence, deficiency of vital energy, deficiency of yin, deficiency of yang and blood stasis. The localization diagnosis showed that location of osteoporosis is bone and corresponds to the kidney, and also involves liver, lung, spleen (stomach) and heart. The diagnostic content has established the specific symptoms and the non-specific symptoms during various stages. Each of the above syndromes could be diagnosed according to a specific combination of its corresponding symptoms or signs. The clinical verification results showed that the total matching ratio of qualitative diagnosis was 80.56% between the diagnoses made according to the criteria and the diagnoses acquired from the experts' experience, and the total matching ratio of localization diagnosis was 85.56%.
Conclusion: The TCM syndrome diagnostic criteria for osteoporosis is generally consistent with TCM clinical practice, worthy of further popularization and application in clinical practice.

Key words: osteoporosis, syndromes, diagnosis specification, traditional Chinese medicine

[1] Han LP, Liu S . Developing regularity of traditional Chinese medicine syndrome on osteoporosis. Zhonghua Zhong Yi Yao Xue Kan. 2008; 26(12):2601-2602. Chinese with abstract in English.
韩丽萍, 刘实 . 骨质疏松症中医证候的演变规律.中华中医药学刊. 2008; 26(12) : 2601-2602.
[2] Xie YM, Zhu YY, Ge JR, Piao HY, Yu J, Wang HM, Chen WH, Xing MR. Study on the TCM general syndrome of osteoporosis based on the clinical epidemiological investigation. Shi Jie Ke Xue Ji Shu Zhong Yi Yao Xian Dai Hua. 2007 ; 9(2): 38-44. Chinese with abstract in English.
谢雁鸣, 朱芸茵, 葛继荣, 朴海垠, 于嘉, 王和鸣, 陈卫衡, 邢美荣. 基于临床流行病学调查的原发性骨质疏松症中医基本证候研究.世界科学技术——中医药现代化. 2007; 9(2): 38-44.
[3] Zheng XY.Guidelines for clinical research on Chinese new herbal medicines (trial implementation). Beijing: China Medical Science Press. 2002 : 356-360. Chinese.
郑筱萸. 中药新药临床研究指导原则.北京:中国医药科技出版社.2002: 356-360.
[4] Group of Diagnosis Standard on Osteoporosis, Osteoporosis Committee of China Gerontological Society. Proposed standard of osteoporosis diagnosis on Chinese (the second draft). Zhongguo Gu Zhi Shu Song Za Zhi.2000 ; 6(1): 1-3. Chinese.
中国老年学学会骨质疏松委员会骨质疏松诊断标准学科组. 中国人骨质疏松症建议诊断标准(第二稿).中国骨质疏松杂志. 2000; 6(1): 1-3.
[5] Deng TT. Diagnostics of traditional Chinese medicine. 5 th ed. Shanghai: Shanghai Scientific and Technical Publishers.1984: 11. Chinese.
邓铁涛. 中医诊断学.第5版.上海:上海科学技术出版社. 1984: 11.
[6] Qian XS. A new discipline of science — the study of open complex giant system and its methodology. Cheng Shi Fa Zhan Yan Jiu.2005; 12(5): 1-8. Chinese with abstract in English.
doi: 10.3969/j.issn.1006-3862.2005.05.001
钱学森. 一个科学新领域——开放的复杂巨系统及其方法论.城市发展研究. 2005; 12(5): 1-8.
doi: 10.3969/j.issn.1006-3862.2005.05.001
[7] Cui X, Dai RW, Li YD. Emergence of collective intelligence in hall for workshop of meta-synthetic engineering. Xi Tong Fang Zhen Xue Bao.2003; 15 (1): 146-153. Chinese.
doi: 10.3969/j.issn.1004-731X.2003.01.041
崔霞,戴汝为,李耀东.群体智慧在综合集成研讨厅体系中的涌现.系统仿真学报. 2003; 15(1): 146-153.
doi: 10.3969/j.issn.1004-731X.2003.01.041
[8] Shen ZY. Research thoughts of the basic theory of traditional Chinese medicine. Zhongguo Zhong Xi Yi Jie He Za Zhi.1997; 17(11): 643-644. Chinese.
沈自尹. 对中医基础理论研究的思路.中国中西医结合杂志. 1997; 17(11): 643-644.
[9] Li DT. Principles of syndromes of traditional Chinese medicine. Sichuan Zhong Yi.2010 ; 28 (12): 24-26. Chinese.
李东涛. 论证候原理.四川中医. 2010; 28(12): 24-26.
[10] Li DT, Ling CQ, Zhu DZ, Yu CQ, Chen Z, Zhai XF, Shen J, Zhang BH, Zhang JF, Lang QB. Study on the quantitative evaluation on the degree of TCM basic syndromes often encountered in patients with primary liver cancer. Zhongguo Zhong Xi Yi Jie He Za Zhi.2007 ; 27(7) : 602-605. Chinese with abstract in English.
doi: 10.3321/j.issn:1003-5370.2007.07.010
李东涛,凌昌全,朱德增,俞超芹,陈喆,翟笑枫,沈婕,张百红,张金峰,郎庆波.原发性肝癌中医常见基本证候轻重程度量化评价研究.中国中西医结合杂志. 2007; 27(7) : 602-605.
doi: 10.3321/j.issn:1003-5370.2007.07.010
[11] Ling CQ, Liu Q, Li DT, Yue XQ, Hou FG, Zhu DZ, Yu CQ, Chen Z, Zhai XF, Yu Y. Study of a qualitative diagnostic criterion for basic syndromes of traditional Chinese medicine in patients with primary liver cancer. J Chin Integr Med.2005; 3(2): 95-98. Chinese with abstract in English.
凌昌全,刘庆,李东涛,岳小强,侯凤刚,朱德增,俞超芹,陈喆,翟笑枫,于洋.原发性肝癌常见中医基本证候定性诊断规范的研究.中西医结合学报. 2005; 3(1): 95-98.
[12] Zhang ZB, Wang YY, Lu AP, Guo L, Wang Y. On combined syndrome differentiation of essential elements of syndrome and syndrome target point corresponding syndromes. Zhong Yi Za Zhi.2006; 47(7): 483-485. Chinese with abstract in English.
doi: 10.3321/j.issn:1001-1668.2006.07.001
张志斌,王永炎,吕爱平,郭蕾,王耘.论证候要素与证候靶点应证组合辨证.中医杂志. 2006; 47(7): 483-485.
doi: 10.3321/j.issn:1001-1668.2006.07.001
[13] Fang ZH, Geng JJ, Zhang YZ, Xia DS, Yin T, Liu JX, Ni YQ. Study on distribution and grouping regularity of TCM syndrome in 1 000 cases of senile osteoporosis. Zhongguo Zhong Yi Yao Xin Xi Za Zhi.2007 ; 14(5): 15-17. Chinese with abstract in English.
doi: 10.3969/j.issn.1005-5304.2007.05.007
方朝晖,耿家金,张有志,夏冬胜,殷韬,刘建新,倪英群.1 000例老年性骨质疏松症证候分布与组合规律研究.中国中医药信息杂志. 2007; 14(5): 15-17.
doi: 10.3969/j.issn.1005-5304.2007.05.007
[14] Huang HX, Chai ST, Huang H, Chen X, Chen YD. Cluster analysis of syndrome patterns of osteoporosis in traditional Chinese medicine. Guangzhou Zhong Yi Yao Da Xue Xue Bao.2007 ; 24(3) : 180-183. Chinese with abstract in English.
黄宏兴,柴生颞,黄红,陈希,陈彦东.骨质疏松症中医证型的聚类分析.广州中医药大学学报. 2007; 24(1): 180-183.
[1] Wan-jun Guo, Yi Wang, Yu Deng, Lin-yan Cheng, Xin Liu, Ruo-fan Xi, Sheng-jie Zhu, Xin-yi Feng, Liang Hua, Kan Ze, Jian-yong Zhu, Dong-jie Guo, Fu-lun Li. Therapeutic effects of the extract of Sancao Formula, a Chinese herbal compound, on imiquimod-induced psoriasis via cysteine-rich protein 61. Journal of Integrative Medicine, 2022, 20(4): 376-384.
[2] Shang-jin Song, Xuan Liu, Qing Ji, Da-zhi Sun, Li-juan Xiu, Jing-yu Xu, Xiao-qiang Yue. Ziyin Huatan Recipe, a Chinese herbal compound, inhibits migration and invasion of gastric cancer by upregulating RUNX3 expression. Journal of Integrative Medicine, 2022, 20(4): 355-364.
[3] Marisa Casal. Improving the health and treatment success rates of in vitro fertilization patients with traditional chinese medicine: need for more robust evidence and innovative approaches. Journal of Integrative Medicine, 2022, 20(3): 187-192.
[4] Ning Guo, Fei Wu, Mei Wu, Yuan Wang, Qing Lang, Xiao Lin, Yi Feng. Progress in the design and quality control of placeboes for clinical trials of traditional Chinese medicine . Journal of Integrative Medicine, 2022, 20(3): 204-212.
[5] Yan-jun Lin, Kun-li Jiao, Bo Liu, Lu Fang, Shu Meng. Antiplatelet and myocardial protective effect of shexiang tongxin dropping pill in patients undergoing percutaneous coronary intervention: A randomized controlled trial. Journal of Integrative Medicine, 2022, 20(2): 126-134.
[6] Joon-ho Lee, Yuan-ji Wei, Zhong-yan Zhou, Yu-ming Hou, Cheng-long Wang, Li-bo Wang, Hong-jin Wu, Yu Zhang, Wei-wei Dai. Efficacy of the herbal pair, Radix Achyranthis Bidentatae and Eucommiae Cortex, in preventing glucocorticoid-induced osteoporosis in the zebrafish model. Journal of Integrative Medicine, 2022, 20(1): 83-90.
[7] Jia-jia Li, Qing Liang, Guang-chun Sun. Traditional Chinese medicine for prevention and treatment of hepatocellular carcinoma: A focus on epithelial-mesenchymal transition. Journal of Integrative Medicine, 2021, 19(6): 469-477.
[8] Rui-jin Qiu, Min Li, Jia-yuan Hu, Jing Chen, Hong-cai Shang. Methods for development of a core outcome set for clinical trials integrating traditional Chinese medicine and Western medicine. Journal of Integrative Medicine, 2021, 19(5): 389-394.
[9] Mao-xing Pan, Chui-yang Zheng, Yuan-jun Deng, Kai-rui Tang, Huan Nie, Ji-qian Xie, Dong-dong Liu, Gui-fang Tu, Qin-he Yang, Yu-pei Zhang. Hepatic protective effects of Shenling Baizhu powder, a herbal compound, against inflammatory damage via TLR4/NLRP3 signalling pathway in rats with nonalcoholic fatty liver disease . Journal of Integrative Medicine, 2021, 19(5): 428-438.
[10] Ning Zhang, Xiao-he Xiao. Integrative medicine in the era of cancer immunotherapy: Challenges and opportunities. Journal of Integrative Medicine, 2021, 19(4): 291-294.
[11] Thomas Efferth, An-long Xu, Roxana Damiescu, Mita Banerjee, Norbert W. Paul, David Y.W. Lee. Can eastern wisdom resolve western epidemics? Traditional chinese medicine therapies and the opioid crisis. Journal of Integrative Medicine, 2021, 19(4): 295-299.
[12] Si-qi Tang, Yun-liang Wang, Zi-ye Xie, Yang Zhang, Yi Guo, Kang-li Gao, Tang-you Mao, Chun-e Xie, Jun-xiang Li, Xiao-yan Gao. Serum metabolic profiling of traditional Chinese medicine syndromes in patients with diarrhea-predominant irritable bowel syndrome. Journal of Integrative Medicine, 2021, 19(3): 274-281.
[13] Miao-yan Shi, Shi-qi Sun, Wei Zhang, Xing Zhang, Gui-hua Xu, Xuan Chen, Zi-jian Su, Xiu-ming Song, Lu-jiong Liu, Yi-bao Zhang, Yi-le Zhang, Meng Sun, Qi Chen, Yan Xue, Hua Lü, Wei-an Yuan, Xiao-rong Chen, Yun-fei Lu. Early therapeutic interventions of traditional Chinese medicine in COVID-19 patients: a retrospective cohort study. Journal of Integrative Medicine, 2021, 19(3): 226-231.
[14] Shu-jun Wei, Qing-man He, Qing Zhang, Kang-hua Fu, Ruo-lan Li, Wei Peng, Yong-xiang Gao. Traditional Chinese medicine is a useful and promising alternative strategy for treatment of Sjogren's syndrome: A review. Journal of Integrative Medicine, 2021, 19(3): 191-202.
[15] Yi Xia, Lu-shao-bo Shi, Jing-hui Chang, Hua-zhang Miao, Dong Wang. Impact of the COVID-19 pandemic on intention to use traditional Chinese medicine: A cross-sectional study based on the theory of planned behavior. Journal of Integrative Medicine, 2021, 19(3): 219-225.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Jin-rong Fu. Establishment of multivariate diagnosis and treatment system of modern gynecology of traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 22-24
[2] Hao Li, Ming-jiang Yao, Wen-ming Zhao, Jie Guan, Lin-lin Cai, Ling Cui. A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment. Journal of Chinese Integrative Medicine, 2008, 6(1): 25-31
[3] Zhi-chun Jin. Problems in establishing clinical guideline for integrated traditional Chinese and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 5-8
[4] SUN Ming-yu, ZUO Jian, DUAN Ji-feng, HAN Jun, FAN Shi-ming, ZHANG Wei, ZHU Li-fang, YAO Ming-hui. Antitumor activities of kushen flavonoids in vivo and in vitro. Journal of Chinese Integrative Medicine, 2008, 6(1): 51-59
[5] Min Cheng, Qiong Feng, Shu-wen Qian, Hui Gao, Cui-qing Zhu. Preliminary assay of p-amyloid binding elements in heart-beneficial recipe. Journal of Chinese Integrative Medicine, 2008, 6(1): 68-72
[6] Ning-qun Wang, Liang-duo Jiang, Zong-xing Li. Research progress in asthma-related quality of life. Journal of Chinese Integrative Medicine, 2008, 6(1): 93-97
[7] Jing-yuan Mao, Chang-xiao Liu, Heng-he Wang, Guang-li Wei , Zhen-peng Zhang, Jie Xing, Wang Xian liang , Ying-fei Bi . Effects of Shenmai Injection on serum concentration and pharmacokinetics of digoxin in dogs with heart failure. Journal of Chinese Integrative Medicine, 2010, 8(11): 1070-1074
[8] Zhi-mei Wang, Bin Zhang. A study on translation of ellipses in Huangdi Neijing from perspective of hermeneutic theory. Journal of Chinese Integrative Medicine, 2010, 8(11): 1097-1100
[9] Gui Yu, Jie Wang. Thinking on building the network cardiovasology of Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(11): 1206-1210
[10] Pedro Saganha João, Doenitz Christoph, Greten Tobias, Efferth Thomas, J. Greten Henry. Qigong therapy for physiotherapists suffering from burnout: a preliminary study. Journal of Chinese Integrative Medicine, 2012, 10(11): 1233-1239