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Journal of Chinese Integrative Medicine ›› 2004, Vol. 2 ›› Issue (6): 429-431.doi: 10.3736/jcim20040608

• Original Clinical Research • Previous Articles     Next Articles

Effect of integrated traditional Chinese and Western medicine therapy on progression of acute renal failure in patients with chronic renal insufficiency: a short-term clinical study

Peng Fu1, Guang Yu1, Xue-qiang Huang2, Jing Xu1, Xiao-bin Mei1, Hao Wu1, Wei-jie Yuan1   

  1. 1. Department of Nephrology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
    2. Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
  • Received:2004-08-19 Online:2004-11-20 Published:2018-10-20

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Objective: To evaluate the effect of integrated traditional Chinese and Western medicine therapy on the progression of acute renal failure in patients with chronic renal insufficiency.Methods: Thirty-two patients with chronic renal insufficiency developed acute renal failure recently were treated with Chinese herbs and western drugs intravenously and clysterizing of Chinese herbs liquid for 30 minutes, and the treatment course was 14 days. Assessment of liver and renal function, blood routine, electrolytes and endogenous creatinine clearance rate (Ccr) was performed before and 2 weeks after the treatment.Results: The levels of hemoglobin (HB), white blood cell count (WBC) and serum electrolytes showed no significant changes after the treatment. The levels of blood urea nitrogen (BUN) and serum creatinine (SCr) decreased, while the level of Ccr increased significantly (P<0.05) after the treatment. The total effective rate was 65.6%.Conclusion: The integrated traditional Chinese and Western medicine therapy can effectively delay the deterioration of renal function in patients with chronic renal insufficiency accompanied by acute renal failure.

Key words: kidney failure, activating blood to remove stasis, integrated traditional Chinese and western medicine

CLC Number: 

  • R692.5

Tab 1

Changes of blood routine, electrolytes and liver function in patients with renal insufficiency before and after treatment ($\bar{x}$±s )"

Detection Before treatment After treatment
Hb （g/L） 107.35±19.28 107.63±28.37
WBC （×109/L） 5.68±1.35 5.52±1.37
K+ （mmol/L） 4.32±0.39 4.28±0.23
Ca2+（mmol/L） 2.26±0.17 2.27±0.24
P3+（mmol/L） 1.24±0.32 1.25±0.31
Mg2+（mmol/L） 0.97±0.14 0.99±0.21
GLU （mmol/L） 5.56±0.87 5.45±1.08
CO2-CP （mmol/L） 23.53±1.64 24.58±2.71
UA （mmol/L） 0.46±0.12 0.44±0.15
ALB (g/L) 43.58±8.26 43.39±7.17
Pro-ALB (mg/L) 316.02±48.62 307.21± 79.46

Tab 2

Changes of renal function indexes in patients with renal insufficiency before and after treatment ($\bar{x}$±s )"

Detection Before treatment After treatment
BUN （mmol/L） 12.4±3.6 10.6±4.7
SCr （μmol/L） 307.6±74.4 239.5±61.3 *
Ccr （ml/min） 27.3±5.6 32.1±6.8 *
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