原发性肝癌患者和健康人“正常舌象”的对比研究

doi:10.3736/jcim20060104

Abstract

Objective

To find out some microscopically visible morphological differences in normal tongue manifestation between patients with primary liver cancer and healthy adults, and provide some beneficial evidences for microcosmic syndrome differentiation of tongue inspection.

Methods

Microcirculations of the tongue tip, which represented the macroscopical normal tongue manifestation, were observed under an optical microscope in patients with primary liver cancer and healthy adults. Exfoliated cells from tongue coating were examined by hematoxylin-eosin staining.

Results

The proportion of normal tongue manifestation was larger in healthy adults (38.89%) than that in patients with primary liver cancer (2.32%). The total score of microcirculation of tongue tip and the maturation index of exfoliated cells from tongue coating were both higher in patients with primary liver cancer than those in healthy adults with normal tongue manifestation (P＜0.01, P＜0.05).

Conclusion

Normal tongue manifestation, which is macroscopically visible, can be observed in both patients with primary liver cancer and healthy adults, but there exists obvious difference in microcosmic view.

Key words: Normal tongue manifestation, Microcirculation, Exfoliated cells from tongue coating, Liver neoplasms

CLC Number:

R241.25

Wei-zhe Deng, Xiao-qiang Yue, Qing Liu, Jing-dong Gao, Rong-zheng Ren, Chang-quan Ling. Comparative study on normal tongue manifestation in patients with primary liver cancer and healthy adults. Journal of Chinese Integrative Medicine, 2006, 4(1): 13-16.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20060104

http://www.jcimjournal.com/EN/Y2006/V4/I1/13

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Group	n	Total numberof papillae	Number of fungiformpapillae	Diameter of fungiformpapilla (μm)	Thickness of fungiformpapilla (μm)
Healthy adult	42	2.06±0.51	0.94±0.14	701.40±119.38	60.41±9.90
Primary liver cancer	24	1.87±0.40	0.71±0.16*	620.42±229.89*	66.97±25.00
Group	n	Number of vesselsin papilla	Diameter of input vessel (μm)	Diameter of output vessel (μm)	Total score of microcirculation
Healthy adult	42	9.56±1.45	10.99±1.60	19.72±2.68	1.70±0.80
Primary liver cancer	24	9.53±2.15	11.71±2.09	18.74±3.31	3.00±1.84**

Group	n	Uncornified cell (%)	Keratinocyte (%)	Hyperkeratotic cell (%)	Maturation index
Healthy adult	42	0.12±0.07	0.80±0.08	0.08±0.06	0.69±0.18
Primary liver cancer	24	0.31±0.17**	0.58±0.16**	0.10±0.08	0.87±0.07*

Comparative study on normal tongue manifestation in patients with primary liver cancer and healthy adults

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