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Journal of Chinese Integrative Medicine ›› 2007, Vol. 5 ›› Issue (2): 147-149.doi: 10.3736/jcim20070209

• Original Clinical Research • Previous Articles     Next Articles

Clinical observation of Ruyiping in preventing recidivation and metastasis of breast cancer

Sheng Liu1, Yong-qiang Hua1, Zhen-ping Sun1, Song Tan2, De-ming Lu1   

  1. 1. Department of Breast Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    2. Department of Oncology, Yantai Hospital of Traditional Chinese Medicine, Yantai, Shangdong Province 265705, China
  • Online:2007-03-31 Published:2007-03-15

Objective: To observe the effect of Ruyiping, a traditional Chinese compound herbal medicine composed of 5 Chinese herbs for removing toxic materials and dissipating nodules from RuningⅡ, another traditional Chinese compound herbal medicine for treating breast cancer, in preventing recidivation and metastasis in breast cancer patients after operation.

Methods: Eighty patients with breast cancer after operation were randomly divided into Ruyiping group and Runing Ⅱ group, and prescribed Ruyiping and Runing Ⅱ on the basis of chemotherapy, radiotherapy and endocrine therapy respectively for two years.

Results: There were two patients with metastasis and three patients lost to follow-up in Ruyiping group and three and two in Runing Ⅱ group. The recidivation and metastasis rates were 5.41% and 7.89% respectively. The difference between the two groups was not statistically significant (P>0.05). The difference of disease-free survival time between the two groups was also not statistically significant.

Conclusion: The effect of Ruyiping in preventing recidivation and metastasis is similar to that of Runing Ⅱ. Ruyiping is the essential component of Runing Ⅱ for preventing recidivation and metastasis. The result provides some clinical evidences for the theory that ''Yudu Pangcuan'' (vestigial poison invasion elsewhere) is the essential pathogenesis of breast cancer's recidivation and metastasis and the utilization of ''Sanjie Jiedu'' (dispersing accumulation and detoxification) is the therapeutic principle in preventing recidivation and metastasis after operation.

Key words: breast cancer, recurrence, metastasis, traditional Chinese medicine

CLC Number: 

  • R226

Figure 1

Comparison of disease free survival time"

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