Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2009, Vol. 7 ›› Issue (4): 366-371.doi: 10.3736/jcim20090412

• Original Experimental Research • Previous Articles     Next Articles

Effects of Fuhuang Shengji Yuchuang Ointment on expressions of types Ⅰ and Ⅲ collagens in granulation tissue of wound in rats with diabetes

XL Xiao,ZY Wang,HJ Tang,XD Liu   

  • Received:2008-09-30 Online:2009-04-20 Published:2009-04-15

Table 1

Effects of FHSJYC Ointment on wound closure index in rats with diabetes(x±s, %)"

Group n Wound closure index
3rd day 11th day
Wound control 7 3.11±1.53 77.62±10.00
NS 6 0.78±0.57* 42.39±9.78*
FHSJYC Ointment 6 2.36±1.30 78.01±8.85

Table 2

Effects of FHSJYC Ointment on expressions of types Ⅰ and Ⅲ collagens in rats with diabetes (x±s, μm2)"

Group n Type Ⅰ collagen Type Ⅲ collagen
3rd day 11th day 3rd day 11th day
Wound control 7 10.06±0.31 10.17±0.62 9.70±0.49 9.95±0.80
NS 6 10.21±0.23 9.44±0.35* 9.06±0.14* 9.09±0.11*
FHSJYC Ointment 6 10.03±0.21 10.20±0.44 10.14±0.44 10.08±0.74
[1] Tang HJ, Li B . Clinical investigation of chronic skin ulcer treated with a compound granulation-promoting and wound-healing oil[J]. Zhong Yi Wai Zhi Za Zhi, 1997,6(4):6-7
唐汉钧, 李斌 . 复黄生肌愈创油膏治疗慢性皮肤溃疡的临床研究[J]. 中医外治杂志, 1997,6(4):6-7
[2] Fu XB, Wang YP, Sun TZ, Yang YH . Preparation of diabetic rat ulcers in rats[J]. Shanghai Shi Yan Dong Wu Ke Xue, 1997,17(4):217-219
付小兵, 王亚平, 孙同柱, 杨银辉 . 糖尿病慢性难愈合创面大鼠模型的制备[J]. 上海实验动物科学, 1997,17(4):217-219
[3] Fu XB, Sun TZ, Sheng ZY . Some kinds of animal models for study of trauma repairing[J]. Zhonghua Shi Yan Wai Ke Za Zhi, 1999,16(5):479-480
付小兵, 孙同柱, 盛志勇 . 几种用于创伤修复研究的动物模型[J]. 中华实验外科杂志, 1999,16(5):479-480
[4] Yu MY, Zhu JG, Tang HJ, Li B, Zhang XL . The pre-paration of Compound Rhubarb Granulation-Promoting and Wound-Healing Oil and effect in treatment of ulcer of lower extremity varices[J]. Zhongguo Yao Shi, 2001,4(2):151-152
俞敏英, 朱景刚, 唐汉钧, 李斌, 章学林 . 复黄生肌愈疮油的配制及其对下肢静脉曲张溃疡的疗效[J]. 中国药师, 2001,4(2):151-152
[5] Fu XB, Wang ZG. Modern new technique and wound healing[M]. Beijing: People's Military Medical Press,2002: 239-248
付小兵, 王正国 . 现代高新技术与创伤修复[M]. 北京: 人民军医出版社,2002: 239-248
[6] Gallant CL, Olson ME, Hart DA . Molecular, histolo-gic, and gross phenotype of skin wound healing in red Duroc pigs reveals an abnormal healing phenotype of hypercontracted, hyperpigmented scarring[J]. Wound Repair Regen, 2004,12(3):305-319
doi: 10.1111/wrr.2004.12.issue-3
[7] Zhang J, Xiang J, Wang ZY, Wang XQ, Lu SL, Liao ZJ . The effect of dermal regeneration template on would collagen synjournal[J]. Shanghai Di Er Yi Ke Da Xue Xue Bao, 2003,23(5):393-395
张剑, 向军, 王志勇, 王西樵, 陆树良, 廖镇江 . 真皮“生物模板”对创面愈合中胶原影响的研究[J]. 上海第二医科大学学报, 2003,23(5):393-395
No related articles found!
Full text



[1] Yi-ting He, Qing-lin Zha, Jian-ping Yu, Yong Tan, Cheng Lu, Ai-ping Lv. Principal factor analysis of symptoms of rheumatoid arthritis and their correlations with efficacy of traditional Chinese medicine and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 32-36
[2] Jun Cai, Hua Wang, Sheng Zhou, Bin Wu, Hua-rong Song, Zheng-rong Xuan. Effect of Sijunzi Decoction and enteral nutrition on T-cell subsets and nutritional status in patients with gastric cancer after operation: A randomized controlled trial. Journal of Chinese Integrative Medicine, 2008, 6(1): 37-40
[3] Wei Zhang, Xiang-feng Lu, Xiao-mei Zhang, Jian-jun Wu, Liang-duo Jiang. A rat model of pulmonary fibrosis induced by infusing bleomycin quickly through tracheal intubation. Journal of Chinese Integrative Medicine, 2008, 6(1): 60-67
[4] A-gao Zhou, Yong Zhang, Gang Kui, De-Yun Kong, Hai-liang Ge, Qiu-hua Ren, Jia-rong Dong, Sheng Hong, Xu-ming Mao, Yin Wang, Hui-zheng Zhang, Shu-jun Wang. Influence of traditional Chinese compound recipes with different efficacy on body weight, tumor weight and immune function in H22 cancer-bearing mice. Journal of Chinese Integrative Medicine, 2008, 6(1): 77-82
[5] Guo-hong Yuan, Xiao-jing Pang, He-chao Ma. Synergic effects of Danggui Buxue Decoction in reducing toxicity of cytoxan in tumor-bearing mice. Journal of Chinese Integrative Medicine, 2008, 6(1): 83-88
[6] Li Zhou, Hong-xing Zhang, Ling-guang Liu, Wen-jun Wan. Effect of electro-acupuncture at Fenglong (GV 16) on nitric oxide and endothelin in rats with hyperlipidemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 89-92
[7] Jin-zhou Tian, Jing Shi, Xin-qing Zhang, Qi Bi, Xin Ma, Zhi-liang Wang, Xiao-bin Li, Shu-li Shen, Lin Li, Zhen-yun Wu, Li-yan Fang, Xiao-dong Zhao, Ying-chun Miao, Peng-wen Wang, Ying Ren, Jun-xiang Yin, Yong-yan Wang, Beijing United Study Group on MCI of the Capital Foundation of Medical Developments. Guiding principles of clinical research on mild cognitive impairment (protocol). Journal of Chinese Integrative Medicine, 2008, 6(1): 9-14
[8] Xin-jun Wang, Ling-ling Wang . A mechanism of endogenous opioid peptides for rapid onset of acupuncture effect in treatment of depression. Journal of Chinese Integrative Medicine, 2010, 8(11): 1014-1017
[9] Bo Wang , Wei Yan , Li-hui Hou, Xiao-ke Wu. Disorder of Tiangui (kidney essence) and reproductive dysfunction in patients with polycystic ovary syndrome. Journal of Chinese Integrative Medicine, 2010, 8(11): 1018-1022
[10] Bing Hu , Hong-mei An , Ke-ping Shen , Qin Du. Senescence-inducing effects of Chinese herbal medicine Tenglong Buzhong Decoction on human colon carcinoma LS-174-T cells and the mechanism. Journal of Chinese Integrative Medicine, 2010, 8(11): 1048-1052