Journal of Chinese Integrative Medicine ›› 2007, Vol. 5 ›› Issue (5): 559-563.doi: 10.3736/jcim20070517
• Original Experimental Research • Previous Articles Next Articles
Effects of melittin on expressions of mitochondria membrane protein 7A6, cell apoptosis-related gene products Fas and Fas Ligand in hepatocarcinoma cells
Chen Zhang, Bai Li, Shu-qin Lu, Yong Li, Yong-hua Su, Chang-quan Ling
- Department of T raditional Chinese Medicine ,Changhai Hospital ,Second Military Medical University , Shanghai 200433 ,China
CLC Number:
- R735.7
| [1] | 张晨, 万旭英, 李柏 , 等. 蜂毒素对肝癌细胞系BEL-7402细胞凋亡的影响[J]. 安徽中医学院学报, 2003,22(4):44-46 |
| Zhang C, Wan XY, Li B , et al. Effect of melittin on apoptosis of hepatocarcinoma cell line BEL-7402[J]. Anhui Zhong Yi Xue Yuan Xue Bao, 2003,22(4):44-46 | |
| [2] | 李柏, 凌昌全, 张晨 , 等. 蜂毒素基因重组腺病毒诱导肝癌细胞凋亡的作用[J]. 中华肝脏病杂志, 2004,12(8):453-455 |
| Li B, Ling CQ, Zhang C . et al. Induced apoptosis of recombinant adenovirus carrying melittin gene for hepatocellular carcinoma cell[J]. Zhonghua Gan Zang Bing Za Zhi, 2004,12(8):453-455 | |
| [3] | 陈永强, 朱振安, 郝永强 , 等. 蜂毒素诱导骨肉瘤细胞U2OS凋亡与坏死的实验研究[J]. 中西医结合学报, 2004,2(3):208-209 |
| Chen YQ, Zhu ZA, Hao YQ . et al. Effect of melittin on apoptsis and necrosis of U2OS cells[J]. Zhong Xi Yi Jie He Xue Bao, 2004,2(3):208-209 | |
| [4] |
Itoh N, Yonehara S, Ishii A , et al. The polypeptide encoded by cDNA for human cell surface antigen Fas can mediate apoptosis[J]. Cell, 1991,66(2):233-243
doi: 10.1016/0092-8674(91)90614-5 pmid: 1713127 |
| [5] | Houghton JA, Harwood FG , Tillman DM.Thymineless death in colon carcinoma cells is mediated via Fas signaling[J].Proc Natl Acad Sci U S A, 1997, 94(): 8144-8149 |
| [6] | 刘岭, 凌昌全, 黄雪强 . 蜂毒素的纯化方法及体外抗肿瘤研究[J]. 中国生化药物杂志, 2003,24(4):163-166 |
| Liu L, Ling CQ, Huang XQ . Study on purification of melittin and its effect on anti-tumor in vitro[J]. Zhongguo Sheng Hua Yao Wu Za Zhi, 2003,24(4):163-166 | |
| [7] | 张晨, 凌昌全, 李柏 , 等. 蜂毒素对肝癌细胞系SMMC7721增殖的影响[J]. 中草药, 2003,34(1):43-45 |
| Zhang C, Ling CQ, Li B . Effect of melittin on proliferation of hepatocarcinoma cell line SMMC7721[J]. Zhong Cao Yao, 2003,34(1):43-45 | |
| [8] | 凌昌全, 李柏, 张晨 , 等. 蜂毒素基因重组腺病毒体内外抗肝癌作用实验[J]. 中华肝脏病杂志, 2004,12(12):741-744 |
| Ling CQ, Li B, Zhang C , et al. Anti-hepatocarcinoma effect of recombinant adenovirus carrying melittin gene[J]. Zhonghua Gan Zang Bing Za Zhi, 2004,12(12):741-744 | |
| [9] |
Ling CQ, Li B, Zhang C , et al. Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma[J]. Ann Oncol, 2005,16(1):109-115
doi: 10.1093/annonc/mdi019 pmid: 15598947 |
| [10] | Zhang C, Ao Z, Seth A , et al. A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells[J]. J Immunol, 1996,157(9):3980-3987 |
| [11] | Koester SK, Roth P, Mikulka WR , et al. Monitoring early cellular responses in apoptosis is aided by the mitochondrial membrane protein-specific monoclonal antibody APO2.7[J]. Cytometry, 1997,29(4):306-312 |
| [12] | 顾伟, 韩克起, 苏永华 , 等. 蟾毒灵对裸鼠人肝癌移植瘤的抑制作用及对Bcl-2和Bax蛋白表达的影响[J]. 中西医结合学报, 2007,5(2):155-159 |
| Gu W, Han KQ, Su YH , et al. Inhibition action of bufalin on human transplanted hepatocellular tumor and its effects on expressions of Bcl-2 and Bax proteins in nude mice[J]. Zhong Xi Yi Jie He Xue Bao, 2007,5(2):155-159 | |
| [13] | Métivier D, Dallaporta B, Zamzami N , et al. Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes[J]. Immunol Lett, 1998,61(2-3):157-163 |
| [14] |
Suda T, Okazaki T, Naito Y , et al. Expression of the ligand in cells of T cell lineage[J]. J Immunol, 1995,154(8):3806-3813
doi: 10.3357/ASEM.21011.2010 pmid: 7706720 |
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