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Journal of Chinese Integrative Medicine ›› 2010, Vol. 8 ›› Issue (12): 1190-1194.doi: 10.3736/jcim20101212

• Literature Research • Previous Articles     Next Articles

Functional targets of Chinese herbal medicine

Bin Xiao,Yun Wang   

  1. Information Engineering Center of Traditional Chinese Herbal Medicine,Beijing University of Chinese Medicine, Beijing 100102, China
  • Received:2010-04-16 Accepted:2010-05-07 Online:2010-12-20 Published:2010-12-15
  • Contact: Yun Wang E-mail:wangyun@bucm.edu.cn

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In order to elucidate the mechanisms of Chinese herbal medicine, much work has been done based on chemical constituent-target in the molecular system. It cannot comply with the holistic efficacy of Chinese herbal medicine. Thus, the authors of this paper proposed to study the functional target adopted from Western medicine. The data of Chinese herbal function were collected from 2005 edition of The People’s Republic of China Pharmacopoeia. A total of 135 functional targets were found, and a network about functional target and mode of action was built. The authors also explored the applications of functional target and the network combined with Sijunzi Decoction and Mahuang Decoction. The results, reflecting the feature of Chinese herbal medicine, will not only be helpful to elucidate the holistic mechanisms of Chinese herbal medicine, but also beneficial to studying the theory of Chinese formulas and developing new formulas.

Key words: Chinese herbal medicine, Functional target, Mechanisms

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编号 功能靶点 出现次数 编号 功能靶点 出现次数 编号 功能靶点 出现次数
1 血 173 46 表 13 91 心火 2
2 热 155 47 脓 13 92 胸 2
3 毒 110 48 窍 12 93 阳气 2
4 湿 107 49 痉 11 94 瘀血 2
5 气 104 50 乳 11 95 元气 2
6 痛 104 51 郁 11 96 智 2
7 风 102 52 疹 11 97 崩 1
8 痰 72 53 逆 10 98 表里 1
9 肝 67 54 呕 10 99 冲 1
10 肿 67 55 汗 9 100 冲任 1
11 肾 57 56 坚 9 101 疮毒 1
12 肺 49 57 疟 9 102 带浊 1
13 尿 48 58 胎 9 103 胆火 1
14 瘀 40 59 翳 8 104 呃 1
15 经 37 60 脉 8 105 耳 1
16 结 35 61 暑 8 106 腐 1
17 水 33 62 痒 8 107 肝火 1
18 中 32 63 痈 8 108 肝热 1
19 阳 31 64 烦 7 109 宫 1
20 肠 29 65 肾阳 7 110 蛔 1
21 脾 29 66 滞 7 111 秽 1
22 神 29 67 痹 6 112 惊搐 1
23 虫 28 68 骨蒸 6 113 漏 1
24 胃 28 69 痢 6 114 满 1
25 寒 27 70 饮 6 115 脑 1
26 咳 26 71 关节 6 116 疱 1
27 络 26 72 精血 5 117 清阳 1
28 津 25 73 带 4 118 热毒 1
29 巨 24 74 胆 4 119 伤 1
30 阴 24 75 发 4 120 酸 1
31 便 23 76 筋 4 121 髓 1
32 火 23 77 痞 4 122 唾 1
33 喘 21 78 癥 4 123 涎 1
34 精 21 79 浊 4 124 心肾 1
35 心 21 80 斑 3 125 虚 1
36 疮 20 81 鼻窍 3 126 虚热 1
37 泻 18 82 风痰 3 127 癖 1
38 积 17 83 骨 3 128 炎 1
39 筋骨 17 84 脱 3 129 腰膝 1
40 惊 17 85 胀 3 130 遗 1
41 肌 15 86 疳热 2 131 郁热 1
42 淋 15 87 黄 2 132 折伤 1
43 咽 15 88 渴 2 133 痔 1
44 食 14 89 头目 2 134 赘疣 1
45 燥 14 90 下 2 135 目翳 1

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