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Journal of Integrative Medicine ›› 2018, Vol. 16 ›› Issue (1): 6-13.doi: 10.1016/j.joim.2017.12.001

• Review • Previous Articles     Next Articles

Research methods in complementary and alternative medicine: An integrative review

Fabiana de Almeida Andrade a, Caio Fabio Schlechta Portella b   

  1. a Anhembi Morumbi University, São Paulo 01423-001, Brazil
    b Department of Naturology, Anhembi Morumbi University, São Paulo 06730-000, Brazil
  • Received:2017-03-02 Accepted:2017-06-01 Online:2018-01-15 Published:2017-12-09
  • Contact: Fabiana de Almeida Andrade; E-mail:

The scientific literature presents a modest amount of evidence in the use of complementary and alternative medicine (CAM). On the other hand, in practice, relevant results are common. The debates among CAM practitioners about the quality and execution of scientific research are important. Therefore, the aim of this review is to gather, synthesize and describe the differentiated methodological models that encompass the complexity of therapeutic interventions. The process of bringing evidence-based medicine into clinical practice in CAM is essential for the growth and strengthening of complementary medicines worldwide.

Key words: Research methodology, Complementary medicine, Alternative medicine, Complementary therapies, Comparative effectiveness research, Outcome assessment, Nonlinear dynamics, Evaluation studies

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