Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2005, Vol. 3 ›› Issue (5): 359-361.doi: 10.3736/jcim20050506

• Original Clinical Research • Previous Articles     Next Articles

A preliminary epidemiological study and discussion on traditional Chinese medicine pathogenesis of chronic fatigue syndrome in Hong Kong

Yan-mun Yiu1,Ming-yi Qiu2   

  1. 1. School of Chinese Medicine, University of Hong Kong, Hong Kong, China
    2. Department of Traditional Chinese Medicine, Hubei College of Traditional Chinese Medicine, Wuhan, Hubei Province 430061, China
  • Received:2005-05-09 Online:2005-09-20 Published:2005-09-20
  • Contact: Yan-mun Yiu E-mail:yoyo@hku.hk

Objective

Our purpose is to conduct an epidemiological study of chronic fatigue syndrome (CFS) and its syndrome types and symptoms of traditional Chinese medicine (TCM) among adults (20-50 years old) in Hong Kong, and to discuss the TCM pathogenesis.

Methods

Design: Cross-sectional questionnaire survey.Measures: Demographic data, CDC (1994) CFS diagnostic criteria, Trudie Chalder fatigue scale, and China national standard for TCM syndrome types criteria.Subjects: Twenty to fifty years old adults by convenient sampling.

Results

One thousand and thirteen subjects were successfully interviewed. Five hundred and eighty-five subjects (57.8%) had different levels of fatigue. Sixty-five subjects (6.4%) met CFS diagnostic criteria. In terms of TCM syndrome types, blood stasis due to qi deficiency had the highest prevalence (35.7%) among CFS. In the 54 symptoms investigated in total, the first eight symptoms in order of appearing rates were soreness of loins and weakness in knees, poor spirit, lassitude, pain, insomnia, forgetting, vessels blood stasis, vertigo and dazzle. The mostly appeared tongue figures were pale and corpulent or pale dim tongue proper, white and white greasy tongue coating, and the mostly appeared pulse figure was sunken-thin.

Conclusion

he point prevalence of CFS among adults of 20 to 50 years old was found to be 6.4%. The most prevalent TCM syndrome type was blood stasis due to qi deficiency. The TCM pathogenesis of CFS was deficiency of origin, mainly deficiency of qi and kidney, with excess of superficiality.

Key words: Chronic fatigue syndrome, Symptom complex, Blood stasis due to qi deficiency

CLC Number: 

  • R181.37
[1] Chalder T, Berelowitz G, Pawlikowska T , et al. Development of a fatigue scale[J]. J Psychosom Res, 1993,37(2):147-153
doi: 10.1016/0022-3999(93)90081-P pmid: 8463991
[2] Fukuda K, Straus SE, Hickie I , et al. The chronic fatigue syndrome: a comprehensive approach to its definition and study[J]. Ann Intern Med, 1994,121(12):953-959
doi: 10.7326/0003-4819-121-12-199412150-00009
[3] 郑筱萸 . 中药新药临床研究指导原则(第1版)[M]. 北京: 中国医药科技出版社, 2002,( 第1版):361-392
[4] Kawakami N, Iwata N, Fujihara S , et al. Prevalence of chronic fatigue syndrome in a community population in Japan[J]. Tohoku J Exp Med, 1998,186(1):33-41
doi: 10.1620/tjem.186.33 pmid: 9915105
[5] Lloyd AR, Hickie I, Boughton CR , et al. Prevalence of chronic fatigue syndrome in an Australian population[J]. Med J Aust, 1990,153(9):522-528
[6] Buchwald D, Umali P, Umali J , et al. Chronic fatigue and the chronic fatigue syndrome: prevalence in a Pacific Northwest health care system[J]. Ann Intern Med, 1995,123(2):81-88
doi: 10.7326/0003-4819-123-2-199507150-00001
[1] Lu Liu, Ying Gao. Study on the correlation between traditional Chinese medicine syndrome and short-term prognosis of ischemic stroke using logistic regression model and repeated-measures analysis of variance. Journal of Chinese Integrative Medicine, 2012, 10(9): 983-990.
[2] Ying-fei Bi , Jing-yuan Mao , Xian-liang Wang , Ya-zhu Hou , Yi-zhu Lu , Shan Bin Soh , Bo-li Zhang. Clinical epidemiology survey of the traditional Chinese medicine etiology and syndrome differentiation of coronary artery disease: Study protocol of a multicenter trial. Journal of Chinese Integrative Medicine, 2012, 10(6): 619-627.
[3] Yu Zhao, Jing-hua Peng , Xue-mei Li , Qi-lin Fu, Tuan Cui , Qi Li, Ya-jun Tang , Qin Feng , Hua Zhang , Hua Zhou , Yi-yang Hu. Diagnostic value of clinical indices in syndrome differentiation of chronic hepatitis B: an exploration based on receiver operating characteristic curves and stepwise discriminant analysis. Journal of Chinese Integrative Medicine, 2012, 10(12): 1382-1387.
[4] Dong-tao Li, Jian Wang , Hong-yang Jiang , Feng-lei Shi , Fu-yu Li , Ji-hong Liu , Yong-mei Cheng , Nan Yan , Ai-hua Hu, Mei-zeng Zhang , Jie Li, Ling-bo Wei , Rong-qin Jiang. Quantitative evaluation of the degrees of traditional Chinese medicine qualitative syndromes of osteoporosis. Journal of Chinese Integrative Medicine, 2012, 10(11): 1254-1262.
[5] Gui-xiang Chu, Qing-guang Chen, Jia-tuo Xu , Bo Yu , Min Zhang , Long-tao Cui , Hong-jin Wu , Zhao-fu Fei. Analysis on pulse diagram characteristics of subjects with subhealth state. Journal of Chinese Integrative Medicine, 2012, 10(10): 1099-1105.
[6] Xing-jiang Xiong, Hai-xia Li . Experience on clinical application of Chinese herbal medicine Yi Guan Jian decoction. Journal of Chinese Integrative Medicine, 2011, 9(8): 920-923.
[7] Ji Sun, Sheng-liang Zhu, Shu-ying Ma, Xiao-su Wang, Jing Kong. Clinical characteristics of patients with reflux esophagitis exhibiting gallbladder heat attacking the stomach or stagnant heat of the liver and stomach syndrome. Journal of Chinese Integrative Medicine, 2011, 9(7): 732-736.
[8] Tian-fang Wang, Xiao-lin Xue, Ya-jing Zhang, Ping Han, Zhen Li, Wen-ping Wang, Jian-min Xing, Qing-bo Wang, Yu Tang, Li Li, Jia-jia Wang, Guan-ru Li, Shao-liang Ji, Liu-xin Wu, Yan Zhao, Xiu-yan Wu, Run-shuan Zhao. Effects of Xiaopi Yishen herbal extract granules in treatment of fatigue-predominant subhealth due to liver-qi stagnation and spleen-qi deficiency: A prospective, randomized, placebo-controlled and double-blind clinical trial. Journal of Chinese Integrative Medicine, 2011, 9(5): 515-524.
[9] Kai Qu, Tian-fang Wang, Yan Zhao, Xiao-lin Xue, Xiu-yan Wu, Hua-liang Deng, Lu Yang, Li-liYu , Hong Yue, Qing-guo Wang. Common syndrome factors of traditional Chinese medicine in chronic renal failure based on the questionnaire investigation among experts. Journal of Chinese Integrative Medicine, 2010, 8(12): 1147-1152.
[10] Chan Chen, Yong-mei Meng , Peng Zhang, Juan Wang, Hui-hui Zhao, Shu-zhen Guo , Wei Wang. Diagnosis and treatment rule of traditional Chinese medicine for syndrome factors of chronic congestive heart failure: a study based on Shannon entropy method. Journal of Chinese Integrative Medicine, 2010, 8(11): 1080-1084.
[11] Wen-juan Wang , Zhi-kui Wu , Xin-hua Zhang , Wen-jun Liu , Yong-mei Liu , Su-ping Fang , Rong-xin Wang , Chong Zhang , Ping-ping Li , Rui-gui Luo . A family survey of syndromes of traditional Chinese medicine in patients with β-thalassemia. Journal of Chinese Integrative Medicine, 2009, 7(2): 116-120.
[12] Zhao-qin Fang, Zhi-qiang Pan, Wen-li Lu, Xiao-mei Liu, Dong-yuan Guan, Chao Liang. Methodology and purposes of establishing mouse and rat models for syndrome differentiation and treatment. Journal of Chinese Integrative Medicine, 2009, 7(10): 907-.
[13] Guo-ping Liu , Yi-qin Wang, Ying Dong, Nai-qing Zhao, Zhao-xia Xu, Fu-feng Li, Hai-xia Yan, Peng Qian, Rui Guo, Xiao-dan Zhang, Dan Di. Development and evaluation of an inquiry scale for diagnosis of heart system syndromes in traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2009, 7(1): 20-24.
[14] Jie Wang, Qing-yong He, Zhan Shi, Yan-wei Xing, Ji Li, Yu-tao Fang, Yan-li Tang. Correlation between syndrome factor combination and cardiac function as well as blood-lipid in coronary heart disease. Journal of Chinese Integrative Medicine, 2008, 6(9): 897-901.
[15] Zhi-qiang Pan, Zhao-qin Fang, Wen-li Lu, Chao Liang, Zhong-hua Wu, Xiao-mei Liu, Li Hou, Hui Zhang, Shao-yuan Zhuo, Ming-juan Liao, Bi-feng Gao. Differentially expressed genes in adrenal gland of H22 liver cancer mice with different syndromes and in different stages. Journal of Chinese Integrative Medicine, 2008, 6(8): 843-851.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Wei-xiong Liang. Problems-solving strategies in clinical treatment guideline for traditional Chinese medicine and integrative medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 1-4
[2] Zhao-guo Li. Discussion on English translation of commonly used sentences in traditional Chinese medicine: part one. Journal of Chinese Integrative Medicine, 2008, 6(1): 107-110
[3] Jun Hu, Jian-ping Liu. Non-invasive physical treatments for chronic/recurrent headache. Journal of Chinese Integrative Medicine, 2008, 6(1): 31
[4] Xue-mei Liu, Qi-fu Huang, Yun-ling Zhang, Jin-li Lou, Hong-sheng Liu, Hong Zheng. Effects of Tribulus terrestris L. saponion on apoptosis of cortical neurons induced by hypoxia-reoxygenation in rats. Journal of Chinese Integrative Medicine, 2008, 6(1): 45-50
[5] . Uniform requirements for manuscripts submitted to biomedical journals: Writing and editing for biomedical publication (Chinese version, part two). Journal of Chinese Integrative Medicine, 2010, 8(11): 1001-1005
[6] Daniel Weber, Janelle M Wheat, Geoffrey M Currie. Inflammation and cancer: Tumor initiation, progression and metastasis,and Chinese botanical medicines. Journal of Chinese Integrative Medicine, 2010, 8(11): 1006-1013
[7] Hong Liu , Guo-liang Zhang, Li Shen , Zhen Zeng, Bao-luo Zhou, Cheng-hai Liu, Guang Nie . Application and evaluation of a pseudotyped virus assay for screening herbs for anti-H5Nl avian influenza virus. Journal of Chinese Integrative Medicine, 2010, 8(11): 1036-1040
[8] Zhao-guo Li . A discussion of English translation of 1995 and 1997 Chinese National Standards of Traditional Chinese Medical Terminologies for Clinical Diagnosis and Treatment. Journal of Chinese Integrative Medicine, 2010, 8(11): 1090-1096
[9] Rui Jin, Bing Zhang. A complexity analysis of Chinese herbal property theory: the multiple formations of herbal property (Part 1). Journal of Chinese Integrative Medicine, 2012, 10(11): 1198-1205
[10] Hui-min Liu, Xian-bo Wang, Yu-juan Chang, Li-li Gu. Systematic review and meta-analysis of randomized controlled trials of integrative medicine therapy for treatment of chronic severe hepatitis. Journal of Chinese Integrative Medicine, 2012, 10(11): 1211-1228