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Journal of Chinese Integrative Medicine ›› 2009, Vol. 7 ›› Issue (4): 309-314.doi: 10.3736/jcim20090403

Special Issue: Traditional Chinese Medicine

• Original Clinical Research • Previous Articles     Next Articles

Application of semi-structured and in-depth interview on optimization of clinical research program in traditional Chinese medicine

Xing Liaoa,Yan-ming Xieb   

  1. a Center for Evidence-based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China
    b Institute of Clinical Basic Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China
  • Received:2008-12-04 Accepted:2009-02-10 Online:2009-04-20 Published:2009-04-15

The paper aims to explore basic steps, regulation and data analysis methods of semi-structured and in-depth interview studies of clinical research in traditional Chinese medicine (TCM), and to provide some helpful information obtained from the examples for decision making in TCM research field. A pilot study was made with eight interviewees and, based on which, a formal one with twelve interviewees was done in this study. All the recordings were transcribed into verbal manuscripts, categorized into different archives and labeled by letter from A to T. Grounded theory for analyzing qualitative data was used in this study, and cross-case analysis was also made on the basis of case-by-case analysis results. Nine theories with central categories were constructed by three coding procedures from grounded theory. Three kinds of relationships, three types of optimized attitude, and three concerns were obtained from the example study. Nine analyzing conceptual graphs and nine theories related to optimization of TCM clinical research program were established finally. The researchers of large national studies were included as interviewees in the study. A comprehensive and critical data analysis from twelve interviewees for in-depth interview was conducted in accordance with current international qualitative research, and a response theory model focused on optimization of TCM clinical research program was established. The study laid the foundation for using semi-structured and in-depth interview for TCM clinical research.

Key words: Traditional Chinese medicine, In-depth interview, Qualitative research, Grounded theory, Methodology research




代码 登录 码号 分析
A1001 临床研究方案 临床研究方案 A首先重点关注了研究二字。反思:探讨部分研究者对“十一五”方案优化课题的理解,进而为方案优化提供参考信息。
A1002 制订 方案优化 A认为的概念或者步骤。反思:该处访谈时,应该追问如何讨论,如何修订,如何修改,如何定稿。
A1003 从起草到讨论、修订、
方案优化 A认为的概念或者步骤。反思:该处访谈时,应该追问如何讨论,如何修订,如何修改,如何定稿。




[1] Wengraf T .Qualitative research interviewing — biographic narrative and semi-structured methods[M].London: Sage Publications, 2001
[2] Pope C, Mays N . Qualitative research in health care(2nd ed)[M]. London: BMJ Books, 2000,( 2nd ed):6-7
[3] Corbin J, Strauss A . Grounded theory research: procedures, canons and evaluative criteria[J]. Qual Sociol, 1990,13(1):3-21
doi: 10.1007/BF00988593
[4] Coyne IT . Sampling in qualitative research. Purposeful and theoretical sampling; merging or clear boundaries?[J]. J Adv Nurs, 1997,26(3):623-630
doi: 10.1046/j.1365-2648.1997.t01-25-00999.x
[5] Chen XM . From one to all: the generalization of qualitative research[J]. Jiao Yu Yan Jiu Yu Shi Yan, 2000,( 2):1-7
陈向明 . 从一个到全体——质的研究结果的推论问题[J]. 教育研究与实验, 2000,( 2):1-7
[6] Patton MQ .Qualitative evaluation and research methods (2nd ed)[M].Newbury Park, CA: Sage Publications, 1990,( 2nd ed)
[7] Liao X, Xie YM . Application of consensus methods in making clinical practice guidelines of traditional medicine[J]. J Chin Integr Med, 2008,6(6):441-446
廖星, 谢雁鸣 . 共识法在传统医学临床实践指南制定过程中的应用探讨[J]. 中西医结合学报, 2008,6(6):441-446
[8] Chen XM . An analysis of native concepts[J]. Wai Yu Jiao Xue Yu Yan Jiu, 2000,32(3):196-199
陈向明 . "本土概念"分析[J]. 外语教学与研究, 2000,32(3):196-199
[9] Strauss AL, Corbin J .Basics of qualitative research: techniques and procedures for developing grounded theory( 2nd ed)[M].London: Sage Publications, 1998,( 2nd ed)
[10] Xie YM, Liao X . Application of consensus methods in making clinical practice guidelines of traditional medicine[J]. J Chin Integr Med, 2008,6(7):668-673
谢雁鸣, 廖星 . 医学研究领域里定性访谈法的质量控制与评估[J]. 中西医结合学报, 2008,6(7):668-673
[11] Lincoln YS, Guba EG .Naturalistic inquiry[M].Beverly Hill, CA: Sage Publications, 1985
[12] Kvale S .Issues of validity in qualitative research[M].Lund, Sweden: Studentlitteratur, 1989
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