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Journal of Chinese Integrative Medicine ›› 2011, Vol. 9 ›› Issue (2): 148-152.doi: 10.3736/jcim20110206

• Original Clinical Research • Previous Articles     Next Articles

An analysis of subhealth status based on partial least squares

Zhong-ping Li1, Yue Su1, Hong-yi Shen1(), Xiao-tian Zhang2, Lin Fan2   

  1. 1. Department of Health Nutrition, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2. International Health Center, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
  • Received:2010-11-03 Accepted:2010-12-12 Online:2011-02-20 Published:2011-02-15
  • Contact: Shen Hong-yi E-mail:Xhhc1503@sina.com

Objective: To explore the discrimination model of subhealth with statistical method of partial least squares (PLS).
Methods: This study was based on the Subhealth State Rating Scale (SHSRS). A total of 88 subhealth subjects (scoring less than 85 in SHSRS) and 64 healthy people (scoring over 85 in SHSRS) were enrolled randomly. Information regarding the clinical symptoms was screened by stepwise regression as independent variables. Mathematical models were established by leave-one-out in PLS program for subhealth recognition before and after stepwise regression respectively. Accuracy rates were observed and compared by using the Visual Basic 6.0.
Results: The practical accuracy rate of PLS models in subhealth recognition was 89.47%, and increased to 92.10% after stepwise regression for variables.
Conclusion: PLS has certain reference value in establishing subhealth discrimination models. It can also play an important part in item selection of the scale.

Key words: subhealth, symptom, mathematical model, partial least squares

[1] Ni HM, He YM, Shen HY, Fang SQ, Xu L, Gao YT, Wu YP . Idea of the evaluation of sub-health state[J]. Yi Xue Yu Zhe Xue Ren Wen Ke Xue Ban, 2008,29(1):5-7
倪红梅, 何裕民, 沈红艺, 方盛泉, 徐丽, 高也陶, 吴艳萍 . 亚健康状态评价构想[J]. 医学与哲学(人文科学版), 2008,29(1):5-7
[2] Xu L, Xia JL, He YM . The rationale of applying structural equation model in research of sub-health status[J]. Yi Xue Yu Zhe Xue Ren Wen Ke Xue Ban, 2008,29(4):36-37
徐丽, 夏结来, 何裕民 . 在亚健康状态研究中运用结构方程模型的合理性[J]. 医学与哲学(人文科学版), 2008,29(4):36-37
[3] Li X, He LY, Liu C . Boosting algorithm and its application of the sub-health classification[J]. Zhongguo Wei Sheng Tong Ji, 2008,25(2):158-161
doi: 10.3969/j.issn.1002-3674.2008.02.013
李霞, 何丽云, 刘超 . Boosting算法及其在中医亚健康数据分类中的应用[J]. 中国卫生统计, 2008,25(2):158-161
doi: 10.3969/j.issn.1002-3674.2008.02.013
[4] Su Y, Guo YL . The novel algorithm for estimation of the number of principal component in partial least-squares method[J]. Ji Suan Ji Yu Ying Yong Hua Xue, 2001,18(3):237-240
doi: 10.3969/j.issn.1001-4160.2001.03.010
苏越, 郭寅龙 . 偏最小二乘法中主成分数确定的新方法[J]. 计算机与应用化学, 2001,18(3):237-240
doi: 10.3969/j.issn.1001-4160.2001.03.010
[5] He YM, Shen HY, Ni HM, Gong P . Study of the category of sub-health[J]. Yi Xue Yu Zhe Xue Ren Wen Ke Xue Ban, 2008,29(1):2-4
何裕民, 沈红艺, 倪红梅, 龚鹏 . 亚健康的范畴研究[J]. 医学与哲学(人文科学版), 2008,29(1):2-4
[6] Xu L, Xia JL, Ni HM, Shen HY, Yin SY, He YM . The preliminary screening of item pool on Chinese sub-health state rating scale[J]. Zhongguo Wei Sheng Tong Ji, 2009,26(1):29-34
doi: 10.3969/j.issn.1002-3674.2009.01.008
徐丽, 夏结来, 倪红梅, 沈红艺, 尹守乙, 何裕民 . 中国人亚健康状态评估表条目的初步筛选[J]. 中国卫生统计, 2009,26(1):29-34
doi: 10.3969/j.issn.1002-3674.2009.01.008
[7] Xie YM, Liu BY, Piao HY, He LY, Li WQ, Hu JQ, Gao RL, He LZ, Gao Y, Feng XZ . Exploration on the common characters of sub-healthy people based on clinical epidemiology[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2006,26(7):612-616
doi: 10.7661/CJIM.2006.7.612
谢雁鸣, 刘保延, 朴海垠, 何丽云, 李文泉, 胡镜清, 高荣林, 何良志, 高颖, 冯兴中 . 基于临床流行病学调查的亚健康人群一般特征的探析[J]. 中国中西医结杂志, 2006,26(7):612-616
doi: 10.7661/CJIM.2006.7.612
[8] Wang L, Su Y, Zhang Q, Liu P, Su SB . Classification and modeling of traditional Chinese medicine syndromes in patients with posthepatitic cirrhosis by partial least-squares[J]. J Chin Integr Med, 2008,6(11):1122-1124
王磊, 苏越, 张琴, 刘平, 苏式兵 . 偏最小二乘法在肝炎后肝硬化中医证候分类建模中的应用[J]. 中西医结合学报, 2008,6(11):1122-1124
[9] Wang HW . Harms to principle component analysis caused by multiple related variables[J]. Beijing Hang Kong Hang Tian Da Xue Xue Bao, 1996,22(1):65-70
王惠文 . 变量多重相关性对主成分分析的危害[J]. 北京航空航天大学学报, 1996,22(1):65-70
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