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Journal of Chinese Integrative Medicine ›› 2003, Vol. 1 ›› Issue (1): 54-56.doi: 10.3736/jcim20030123

Special Issue: Acupuncture & Moxibustion

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Comparative experimental study on treatment of rat's injured sciatic nerve with electroacupuncture and Buyang Huanwu Decoction

Shui-jin Shao(), Bao-zhi Shan, Jun Jiang, Zhen-guo Yan   

  1. Department of Anatomy, Shanghai University of Traditional Chinese Medicine, Shanghai 200032,China
  • Received:2003-01-18 Online:2003-03-20 Published:2018-10-19

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Objective

To study the effect of the electroacupuncture and Buyang Huanwu Decoction (BYHWD) on the regeneration of the rat's injured sciatic nerve.


Methods

Rat's sciatic nerve injury model was made by operation. The rats were treated with electroacupuncture or BYHWD and their nerve electro-physiological indices and histological changes tested by HRP were observed.


Results

It was demonstrated that the recovery ratios of nerve conduction velocity and muscle evoked action potential of the group treated with electroacupuncture and the group treated with BYHWD were higher than those of the group treated with western medicine or the group without treatment. The differences were significant. The labeling cells in anterior horn of spinal marrow and spinal ganglion of the group treated with electroacupuncture and the group treated with BYHWD were more abundant than those of the group treated with western medicine or the group without treatment. The differences were significant. The effect of electroacupuncture was better than that of the BYHWD.


Conclusion

It suggests that both electroacupuncture therapy and BYHWD can promote the recovery of the function in early stage of injured nerve, and they are effective methods for promoting the regeneration of injured peripheral nerve.

Key words: trauma, nervous system, electroacupuncture, Buyang Hanwu Decoction, neurophysiology, HRP

CLC Number: 

  • R651.3

"

组别 n MCV' MAP'
电针组 12 50.90±9.43**△△ 51.09±8.10**△△
中药组 10 47.62±5.56**△△ 45.02±8.87**△△
西药组 11 33.34±5.90 26.94±7.93
空白组 9 35.49±5.34 26.54±4.99

"

组别 n L4 L5
电针组 9 12.44±2.24**△△▲▲□□ 10.11±1.62**△△▲▲□□
中药组 9 9.67±1.58**△△ 7.56±1.51**△△
西药组 9 6.69±1.50 5.11±1.36
空白组 9 5.67±1.00 4.00±0.87
正常组 9 15.87±2.18 13.23±1.71

"

组别 n L4 L5
电针组 6 110.17±13.21**△▲▲ 89.83±8.82*△▲▲
中药组 6 99.83±11.85* 82.67±9.24*
西药组 6 94.00±9.63 74.17±9.06
空白组 6 82.33±10.44 66.00±9.21
正常组 6 135.32±14.01 112.14±10.15
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