Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2006, Vol. 4 ›› Issue (5): 482-484.doi: 10.3736/jcim20060508

• Original Clinical Research • Previous Articles     Next Articles

Correlation between the width of lingual vein and the changes of hemodynamics of portal system in patients with primary liver cancer

Xiao-qiang Yue1,Jing-dong Gao1,Xiao-feng Zhai1,Qing Liu1,Dong Jiang2,Chang-Quan Ling1, 3   

  1. 1. Department of Traditional Chinese Medicine, Second Military Medical University, Shanghai 200433, China
    2. Department of Ultrasonics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
    3. E-institutes of Internal Medicine of Traditional Chinese Medicine of Shanghai Municipal Education Commission, Shanghai, 201203 China
  • Online:2006-09-30 Published:2018-10-21


To explore the correlation between the width of lingual varix and changes of hemodynamics of portal system in patients with primary liver cancer so as to supply the data for the forecast of portal hypertension by observing lingual varix.


The diameter of lingual vein (Dlv) was measured by vernier caliper as dependent variable, and the diameters and indexes of hemodynamics of portal vessels were measured by Doppler as independent variables, then a multipe stepwise analysis was performed.


The diameters of portal vein (Dpv) and splenic vein (Dsv) entered the formula Dlv (mm)=0.185+0.311 Dsv (mm) +0.236 Dpv (mm) when the entry and removal values were αin=0.10 and αout=0.15, respectively.


The width of lingual vein is closely correlated with the diameters of portal vein and splenic vein in patients with primary liver cancer.

Key words: Lingual vein, Portal system, Portal hypertension, Liver neoplasms

CLC Number: 

  • R241.25

Table 1

Analysis of variance of the regression formula"

Sum of squares Df Mean square F value P value
Regression 6.723 2 3.361 5.717 0.006
Residual 28.809 77 0.588
Total residual 35.532 79

Table 2

Regression coefficients and their checking results of the independents entered the regression formula"

Independents Unstandardized coefficients Standard error Standardized coefficients t value P value
Constant 0.185 0.791 0.234 0.816
Dsv 1.446 0.617 0.311 2.345 0.023
Dpv 1.141 0.641 0.236 1.780 0.081
[1] 刘庆, 岳小强, 任荣政 , 等. 不同临床分期原发性肝癌患者的舌下络脉特征[J]. 中西医结合学报, 2004,2(3):175-177
doi: 10.3969/j.issn.1006-5725.2011.21.052
[2] 靳士英, 薛红仙 . 慢性严重肝病舌脉诊临床意义的探讨[J]. 实用医学杂志, 1997,13(9):622-623
[3] 李乃民, 林晓东, 王淑英 , 等. 运用观察舌脉曲张的方法诊断门脉高压的临床与实验研究[J]. 中国中西医结合外科杂志, 1994,1(1):2-5
[1] Xuanbin Wang, Ning Wang, Fan Cheung, Lixing Lao, Charlie Li, Yibin Feng. Chinese medicines for prevention and treatment of human hepatocellular carcinoma: Current progress on pharmacological actions and mechanisms. Journal of Integrative Medicine, 2015, 13(3): 142-164.
[2] Qing-bo Lang, Dong-xia Zhai , Feng Huang, Jian-guo Chen, Yong-hui Zhang, Qun Liu, Xiao-feng Zhai , Bai Li, Chang-quan Ling. Investigation on traditional Chinese medicine syndrome distribution of 4 618 hepatitis B virus infection subjects in Qidong of Jiangsu Province, China. Journal of Chinese Integrative Medicine, 2012, 10(5): 525-531.
[3] Li Weng, Juan Du, Wen-ring He, Chang-quan Ling. Characteristic genomics of peripheral blood mononuclear cells of hepatocellular carcinoma patients with liver-kidney yin deficiency syndrome. Journal of Chinese Integrative Medicine, 2012, 10(4): 406-415.
[4] Ying Xu , Chang-chun Zeng , Xiu-yu Cai , Rong-ping Guo , Guang Nie , Ying Jin. Chromaticity and optical spectrum colorimetry of the tongue color in different syndromes of primary hepatic carcinoma. Journal of Chinese Integrative Medicine, 2012, 10(11): 1263-1271.
[5] Xiao-bing Li, Xiao-juan He, Biao Liu, Li Xu, Da-hong Ju, Miao Jiang, Ai-ping Lu. Immunoregulatory function of Radix Glycyrrhizae polysaccharide in tumor-bearing mice. Journal of Chinese Integrative Medicine, 2010, 8(4): 363-367.
[6] Yan Wang , Li-wu Lin, Zhi-kui Chen, En-sheng Xue, Xiao-dong Lin, Li-yun Yu, Zhen-hu Lin. Effects of intratumoral injection of microspheres containing cobra venom cytotoxin on transplanted human hepatoma in nude mice. Journal of Chinese Integrative Medicine, 2009, 7(9): 836-841.
[7] Bai-yu Li, Li-na Wang, Xiao-qiang Yue, Bai Li. Characteristics of sublingual vein and expressions of vascular endothelial growth factor and hypoxia-inducible factor 1α proteins in sublingual tissues of Beagle dogs with portal hypertension. Journal of Chinese Integrative Medicine, 2009, 7(5): 463-467.
[8] Zhi-kui Chen, Li-wu Lin, Fa-duan Yang, Xiu-hua Weng, Hua-jing Cai, En-sheng Xue, Yan Wang. Effects of interstitial chemotherapy using thermosensitive gel-coated ricin on hepatoma H22-bearing mice. Journal of Chinese Integrative Medicine, 2009, 7(5): 447-452.
[9] Xian-bo Wang, Ping Liu, Zhi-peng Tang, Feng-hua Li, Cheng-hai Liu, Yi-yang Hu, Lie-ming Xu. Cordyceps mycelia extract decreases portal hypertension in rats with dimethylnitrosamine-induced liver cirrhosis: a study on its histological basis. Journal of Chinese Integrative Medicine, 2008, 6(11): 1136-1144.
[10] Wei Gu, Ke-qi Han, Yong-hua Su, Xue-qiang Huang, Chang-quan Ling. Inhibition action of bufalin on human transplanted hepatocellular tumor and its effects on expressions of Bcl-2 and Bax proteins in nude mice. Journal of Chinese Integrative Medicine, 2007, 5(2): 155-159.
[11] Qi Li​, Zhong-ze Fan​, Xian-qian Li​, Xiao-hua Liu​, Jue Sun​, Wei Gu​, Paul Heng​, Hong Gao​. Effects of interventional therapy with norcantharidin microsphere on hepatoma in rats and its mechanism. Journal of Chinese Integrative Medicine, 2006, 4(4): 378-383.
[12] Wei-zhe Deng, Xiao-qiang Yue, Qing Liu, Jing-dong Gao, Rong-zheng Ren, Chang-quan Ling. Comparative study on normal tongue manifestation in patients with primary liver cancer and healthy adults. Journal of Chinese Integrative Medicine, 2006, 4(1): 13-16.
[13] Li-xia Ju, Zhe Chen, Rong-zheng Ren. Progress in research on the treatment of primary liver cancer with traditional Chinese medicine for activating blood to resolve stasis. Journal of Chinese Integrative Medicine, 2005, 3(6): 491-494.
[14] Qing Liu, Yan-bo Zhang, Chuan-hong Ma, Xiao-qiang Yue, Chang-quan Ling. Analysis of literature on therapeutic methods and medicines of traditional Chinese medicine for primary liver cancer. Journal of Chinese Integrative Medicine, 2005, 3(4): 260-262.
[15] Zhen Chen, Lu-ming Liu, Yi-bei He. Correlation between TXB2, 6-Keto-PGF1α and liver metastasis in rats model with blood stasis. Journal of Chinese Integrative Medicine, 2003, 1(3): 199-201.
Full text



[1] Dong Yang, Yong-ping Du, Qing Shen, Wei Chen, Yan Yu, Guang-lei Chen. Expression of alpha-smooth muscle actin in renal tubulointerstitium in patients with kidney collateral stasis. Journal of Chinese Integrative Medicine, 2008, 6(1): 41-44
[2] Hai-feng Wei, Bai-liu Ya, Ling Zhao, Cui-fei Ye, Li Zhang, Lin Li. Evaluation of tongue manifestation of blood stasis syndrome and its relationship with blood rheological disorder in a rat model of transient brain ischemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 73-76
[3] Xi Lin, Jian-ping Liu. Herbal medicines for viral myocarditis. Journal of Chinese Integrative Medicine, 2008, 6(1): 76
[4] Xi Lin, Jian-ping Liu. Tai chi for treating rheumatoid arthritis. Journal of Chinese Integrative Medicine, 2008, 6(1): 82
[5] Liang-ping Hu, Hui Gao. Discrimination of errors in statistical analysis of medical papers published in the first issue of 2006 in Journal of Chinese Integrative Medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 98-106
[6] Yan-bo Zhu , Qi Wang, Cheng-yu Wu, Guo-ming Pang, Jian-xiong Zhao, Shi-lin Shen, Zhong-yuan Xia , Xue Yan . Logistic regression analysis on relationships between traditional Chinese medicine constitutional types and overweight or obesity. Journal of Chinese Integrative Medicine, 2010, 8(11): 1023-1035
[7] Wei Xu, Meng Shi, Jian-gang Liu, Cheng-long Wang . Collagen protein expressions in ischemic myocardium of rats with acute myocardial infarction and effects of qi-tonifying, yin-tonifying and blood-activating herbs and detoxifying and blood-activating herbs. Journal of Chinese Integrative Medicine, 2010, 8(11): 1041-1047
[8] Tao Wang , Feng Qin. Effects of Chinese herbal medicine Xiaoyao Powder on monoamine neurotransmitters in hippocampus of rats with postpartum depression. Journal of Chinese Integrative Medicine, 2010, 8(11): 1075-1079
[9] Ying Xu , Chang-chun Zeng , Xiu-yu Cai , Rong-ping Guo , Guang Nie , Ying Jin. Chromaticity and optical spectrum colorimetry of the tongue color in different syndromes of primary hepatic carcinoma. Journal of Chinese Integrative Medicine, 2012, 10(11): 1263-1271
[10] Xiang-ying Mao , Qin Bian , Zi-yin Shen. Analysis of the osteogenetic effects exerted on mesenchymal stem cell strain C3H10T1/2 by icariin via MAPK signaling pathway in vitro. Journal of Chinese Integrative Medicine, 2012, 10(11): 1272-1278