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Journal of Chinese Integrative Medicine ›› 2008, Vol. 6 ›› Issue (9): 964-967.doi: 10.3736/jcim20080918

• Clinical Experience • Previous Articles     Next Articles

Integrated traditional Chinese and Western medicine in treating 31 cases of myasthenia gravis

Song-lin Cheng1(), Xiao-yun Liu2, Wei-xi Zhang1   

  1. 1. Department of Neurology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province 510080, China
    2. Department of Traditional Chinese Medicine, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province 510080,China
  • Received:2008-01-21 Online:2008-09-20 Published:2008-09-15

Key words: myasthenia gravis, integrated traditional Chinese and Western medicine therapy, treatment outcome

CLC Number: 

  • R746.1

Table 1

Variation of humoral immune indexes in MG patients during the medication"

Stage of treatment n IgG (x±s, g/L) IgA (x±s, g/L) IgM (x±s, g/L) C3 (x±s, g/L) C4 (median, g/L)
Before treatment 26 10.9±2.92 1.85±0.92 1.21±0.73 0.90±0.62 0.17
The end of the first stage 26 10.2±2.75 1.60±0.81 1.11±0.52 0.93±0.73 0.27
The end of the second stage 26 10.5±2.63 1.55±0.78 0.90±0.65 0.95±0.52 0.19
The end of the third stage 26 9.8±2.55 1.58±0.95 1.09±0.28 1.01±0.71 0.23
The end of the fourth stage 26 11.3±2.47 1.93±0.68 1.33±0.53
[1] Wang XY, Xu XH, Sun H , et al. A clinical absolute and relative score system for myasthenia gravis[J]. Zhonghua Shen Jing Ke Za Zhi, 1997,30(2):87-90
doi: 10.1007/s00376-997-0061-6
王秀云, 许贤豪, 孙宏 , 等. 重症肌无力病人的临床绝对评分法和相对评分法[J]. 中华神经科杂志, 1997,30(2):87-90
doi: 10.1007/s00376-997-0061-6
[2] Li LQ, Sun SG, Xu JZ , et al. A study of the effect of glucocorticosteroid to the cellular and humoral immunity of myasthenia gravis patients[J]. Lin Chuang Nei Ke Za Zhi, 2004,21(5):334-336
doi: 10.3969/j.issn.1001-9057.2004.05.017
李罗清, 孙圣刚, 徐金枝 , 等. 糖皮质激素对重症肌无力患者细胞和体液免疫功能影响的研究[J]. 临床内科杂志, 2004,21(5):334-336
doi: 10.3969/j.issn.1001-9057.2004.05.017
[3] Qi GY, Li XL . Clinical observation of integrated traditional Chinese and Western medicine in treating myasthenia gravis[J]. Zhongguo Lin Chuang Yi Sheng Za Zhi, 2007,35(5):57-60
doi: 10.3969/j.issn.1008-1089.2007.05.024
乞国艳, 李晓玲 . 中西医结合治疗重症肌无力的临床观察[J]. 中国临床医生杂志, 2007,35(5):57-60
doi: 10.3969/j.issn.1008-1089.2007.05.024
[4] Liu P, Zhang YY, Qiao J . Establishment and analysis of serum two-dimensional gel electrophoresis profiles of myasthenia gravis patients with spleen and kidney deficiency syndrome[J]. Zhong Xi Yi Jie He Xue Bao, 2007,5(2):150-154
刘萍, 章怡祎, 乔健 . 脾肾虚型重症肌无力患者血清双向电泳图谱的建立及分析[J]. 中西医结合学报, 2007,5(2):150-154
[5] Han T . Abstract to the research of integrated traditional Chinese and Western medicine in treating myasthenia gravis[J]. Zhong Yi Yao Xue Kan, 2003,21(1):139-140
韩涛 . 中西医结合治疗重症肌无力研究探要[J]. 中医药学刊, 2003,21(1):139-140
[6] Zhang L, Wu J, Wang L , et al. Treatment of ocular myasthenia gravis in children with integrated traditional Chinese medicine and Western medicine[J]. Shenzhen Zhong Xi Yi Jie He Za Zhi, 2007,17(3):172-174, 176
doi: 10.3969/j.issn.1007-0893.2007.03.015
张莉, 吴进, 王莉 , 等. 中西医结合治疗儿童眼肌型重症肌无力76例[J]. 深圳中西医结合杂志, 2007,17(3):172-174, 176
doi: 10.3969/j.issn.1007-0893.2007.03.015
[7] Mao HY, Liu SP, Bao SZ . Experimental research progress of splenasthenic syndrome[J]. Zhejiang Zhong Yi Za Zhi, 2007,42(10):612-614
doi: 10.3969/j.issn.0411-8421.2007.10.039
毛海燕, 刘斯平, 包素珍 . 脾虚证的实验研究进展[J]. 浙江中医杂志, 2007,42(10):612-614
doi: 10.3969/j.issn.0411-8421.2007.10.039
[8] Luo J, Gu HY, Xu GX . Regulation of functional immunity in mice with spleen-deficiency with Buzhong Yiqi tang[J]. Zhongguo Xian Dai Yi Xue Za Zhi, 2006,16(17):2613-2615
doi: 10.3969/j.issn.1005-8982.2006.17.014
罗晶, 顾红缨, 徐国宪 . 补中益气汤对脾虚小鼠免疫功能的调节[J]. 中国现代医学杂志, 2006,16(17):2613-2615
doi: 10.3969/j.issn.1005-8982.2006.17.014
[9] Zhang Z, Chen JG . Consideration of the nourishing yin effect of Liuwei Dihuang Pill[J]. Zhong Cheng Yao, 2006,28(8):1244-1245
doi: 10.3969/j.issn.1001-1528.2006.08.057
张尊, 陈建国 . 六味地黄丸滋阴功效的思考[J]. 中成药, 2006,28(8):1244-1245
doi: 10.3969/j.issn.1001-1528.2006.08.057
[10] Xu Y, Yang JR, Bian GW . Immunomodulatory effects of Liu Wei Di Huan Tang on hydrocortisone model mice[J]. Xian Dai Zhong Xi Yi Jie He Za Zhi, 2000,9(13):1204-1206
徐瑶, 杨解人, 卞国武 . 六味地黄汤对氢化可的松模型小鼠的免疫调节作用[J]. 现代中西医结合杂志, 2000,9(13):1204-1206
[11] Xu Q, Du BY, Luo H , et al. Inhibitory effect of Liuwei Dihuang Decoction on lymphocyte apoptosis in immune organ of glucocorticoid-induced kidney-yin-deficiency animal model[J]. Guangzhou Zhong Yi Yao Da Xue Xue Bao, 2000,17(3):207-208
doi: 10.3969/j.issn.1007-3213.2000.03.005
徐勤, 杜标炎, 罗惠 , 等. 六味地黄汤对糖皮质激素肾阴虚模型免疫器官淋巴细胞凋亡的抑制作用[J]. 广州中医药大学学报, 2000,17(3):207-208
doi: 10.3969/j.issn.1007-3213.2000.03.005
[12] Zou Q, Wang RP . Zishen Yutai Pill[J]. Guangdong Yao Xue, 2002,12(2):56
邹琦, 王如萍 . 滋肾育胎丸[J]. 广东药学, 2002,12(2):56
[13] Liu WB, Men LN, Xia Q , et al. Clinical value of the immune parameters in patients with myasthenia gravis[J]. Zhonghua Yi Xue Za Zhi, 2006,86(47):3331-3334
刘卫彬, 门丽娜, 夏强 , 等. 重症肌无力患者免疫指标检测及其临床评价[J]. 中华医学杂志, 2006,86(47):3331-3334
[14] Limburg PC, The TH, Hummel-Tappel E , et al. Antiacetylcholine receptor antibodies in myasthenia gravis. Relation to clinical parameters in 250 patients[J]. J Neurol Sci, 1983,58(23):357-370
doi: 10.1111/j.1749-6632.1993.tb22884.x pmid: 6197385
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