解郁活血方对脑梗死后抑郁症患者神经功能康复的影响

doi:10.3736/jcim20040309

Abstract

Objective: To study the influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction. Methods: Fifty four patients suffered from the depression after acute cerebral infarction were randomly divided into three groups: depression control group, fluoxetine treated group and Jieyu Huoxue Decoction treated group. Eighteen patients of cerebral infarction without depression were enrolled in the no depression control group randomly. The Zung self-rating depression scale (SDS), the modified Edinburgh-Scandinavia stroke scale (MESSS) and the activities of daily living (ADL) were evaluated before treatment, 30 and 60 days after treatment. Results: After 30 and 60 days of treatment, SDS evaluation of the Jieyu Huoxue Decoction treated group showed significant difference as compared with the condition before treatment and that of the depression control group (P＜0.05 or P<0.01), MESSS evaluation and ADL evaluation also showed significant difference as compared with the condition before treatment and that of the depression control group (P＜0.05 or P<0.01); there was no obvious difference between the fluoxetine treated group and the Jieyu Huoxue Decoction treated group, but the Jieyu Huoxue Decoction treated group showed fewer symptoms and less side effect. Conclusion: Jieyu Huoxue Decoction can not only relieve depression after cerebral infarction, but also improve neurological functions.

Key words: Jieyu Huoxue Decoction, cerebral infarction, depression, rehabilitation

CLC Number:

R692

Bei-lei Feng, Qiao-chu Wang, Zheng-yuan Li. Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction. Journal of Chinese Integrative Medicine, 2004, 2(3): 182-184.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20040309

http://www.jcimjournal.com/EN/Y2004/V2/I3/182

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References 7

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Group	n	Before treatment	30 d after treatment	60 d after treatment
No depression control	15	30.2±4.2	27.1±4.3	25.8±3.7
Depression control	16	48.8±5.7	43.5±5.2	41.1±4.7^△
Fluoxetine treated	16	48.1±6.13	6.9±4.3^▲▲	34.9±4.6^△▲▲
Jieyu Huoxue Decoction treated	17	48.2±5.83	5.9±4.1^▲▲	32.9±5.1^△▲▲

Group	n	Before treatment	30 d after treatment	60 d after treatment
No depression control	15	21.1±5.2	14.6±4.2^▲▲	9.4±4.2^△▲▲
Depression control	16	23.3±5.9	18.6±5.2	14.4±2.2^△
Fluoxetine treated	16	23.9±5.5	13.6±5.1^▲▲	9.1±3.2^△▲▲
Jieyu Huoxue Decoction treated	17	23.5±6.2	13.9±4.9^▲▲	9.3±5.2 ^△▲▲

Group	n	Before treatment	30 d after treatment	60 d after treatment
No depression control	15	25.4±3.5	21.8±2.6^▲▲	19.8±4.2^△▲▲
Depression control	16	29.9±2.9	25.8±3.2	23.8±4.2^△
Fluoxetine treated	16	28.9±3.6	20.8±5.1^▲▲	19.1±3.2^△▲▲
Jieyu Huoxue Decoction treated	17	28.5±4.5	20.3±4.2^▲▲	19.4±2.2^△▲▲

Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction

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