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Journal of Chinese Integrative Medicine ›› 2010, Vol. 8 ›› Issue (11): 1018-1022.doi: 10.3736 jcim20101103

• Review • Previous Articles     Next Articles

Disorder of Tiangui (kidney essence) and reproductive dysfunction in patients with polycystic ovary syndrome

Bo Wang,Wei Yan,Li-hui Hou,Xiao-ke Wu   

  1. Department of Gynaecology and Obstetrics, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin 150040,Heilongjiang Province, China
  • Received:2009-03-19 Accepted:2010-05-07 Online:2010-11-20 Published:2010-11-15
  • Contact: Xiao-ke Wu E-mail:xiaokewu2002@vip.sina.com

Traditional Chinese medicine (TCM) usually views polycystic ovary syndrome (PCOS) as a menstrual disease or infertility disease. Reproductive dysfunction in PCOS is characterized by ovarian androgen excess and disturbance of follicular development, and its main clinical manifestations include delayed menstruation, scant menstruation, amenorrhea or infertility. Insulin resistance is a key pathological mechanism of PCOS. “Tiangui”(kidney essence) as a sex-stimulating essence in female in TCM theory, is essential to the menstruation and pregnancy of women. The disturbance of Tiangui (including time, status and rhythm) would result in female reproductive problems. Current studies of Tiangui indicate that ovary is the target organ of PCOS treatment, and its functional characteristics are consistent with the properties of Tiangui in time frame, state form and rhythm cycle. It is then concluded that ovarian dysfunction in PCOS can be expressed as disorder of Tiangui.

Key words: Polycystic ovary syndrome, Tiangui, Reproduction

[1] Deng LW, Wei GH, Pei HG, Zeng Q . Exploring the mechanism of Tiangui modulating genetic process based on genome. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2007; 13(5) : 390-391. Chinese.
邓琳雯, 魏国华, 裴红鸽, 曾倩 . 从基因组视角探讨 “天癸”对遗传过程的调控机制——从分子遗传学入手研究中医遗传学理论.中国中医基础医学杂志. 2007; 13(5) : 390-391.
[2] Ye YP. Discussion on Tiangui. Zhonghua Zhong Yi Yao Xue Kan. 2007; 25(9):1808-1809. Chinese.
叶一萍 .天癸论. 中华中医药学刊. 2007; 25(9):1808-1809.
[3] Jiang HS. Exploration of Tiangui theory. Zhong Yi Za Zhi. 2000; 41(11):645-648. Chinese.
江海身 . 天癸学说探讨.中医杂志. 2000; 41(11):645-648.
[4] Wu JH, Yu CQ, Zhou QL, Han J, Wang ZZ, Shen W. Clinical study on effect of Bushen Huayu Qutan Recipe in treating polycystic ovarian syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 ; 27(10):883-886. Chinese with abstract in English.
doi: 10.3321/j.issn:1003-5370.2007.10.007
吴建辉, 俞超芹, 周巧玲, 韩洁, 王针织, 沈慰 . 补肾化瘀祛痰方治疗多囊卵巢综合征的临床研究. 中国中西医结合杂志. 2007; 27(10):883-886.
doi: 10.3321/j.issn:1003-5370.2007.10.007
[5] Zhang QP. Adjusting menstruation mainly by supplementing kidney and activating blood. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2003; 9(12) : 65-66. Chinese.
doi: 10.3969/j.issn.1006-3250.2003.12.028
章巧萍 . 调经重在补肾活血.中国中医基础医学杂志. 2003; 9(12) : 65-66.
doi: 10.3969/j.issn.1006-3250.2003.12.028
[6] Hao JH, Tao FB . Advance of pubescent phase and lifelong health. Zhongguo Xue Xiao Wei Sheng. 2008; 29(5):388-390. Chinese.
郝加虎, 陶芳标 . 青春发动时相提前与终身健康.中国学校卫生. 2008; 29(5):388-390.
[7] Chen R, Lin SQ. Clinical evolution of polycystic ovary syndrome. Zhongguo Shi Yong Fu Ke Yu Chan Ke Za Zhi. 2007; 23(9):727-730. Chinese.
陈蓉, 林守清 . 多囊卵巢综合征的临床演变.中国实用妇科与产科杂志. 2007; 23(9):727-730.
[8] Wu XK . Polycystic ovary syndrome may be primary follicle disease. Zhongguo Shi Yong Fu Ke Yu Chan Ke Za Zhi. 2007; 23(9):660-663. Chinese.
doi: 10.3969/j.issn.1008-8199.2006.11.025
吴效科 . 多囊卵巢综合征可能是原发性卵泡病.中国实用妇科与产科杂志. 2007; 23(9):660-663.
doi: 10.3969/j.issn.1008-8199.2006.11.025
[9] Wang YY, Zhang ZB . Re-discussion on the key points in improvement of differentiation methodology of TCM. Tianjin Zhong Yi Yao. 2007 ; 24(1):1-4. Chinese with abstract in English.
doi: 10.3969/j.issn.1672-1519.2007.01.001
王永炎, 张志斌 . 再议完善辨证方法体系的几个问题. 天津中医药. 2007; 24(1):1-4.
doi: 10.3969/j.issn.1672-1519.2007.01.001
[10] Hou LH. Wang XB, Wu XK. Discussing anovuation in polycystic ovary syndrome from the theory of a phlegm accumulating in uterus”. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2008; 14(10) : 725-726. Chinese.
侯丽辉, 王晓冰, 吴效科 . 从“痰壅胞宫”病机理论论多囊卵巢综合征排卵障碍.中国中医基础医学杂志. 2008; 14(10) : 725-726.
[11] Suo YP, Wang L, Chen HZ, Wang XX. Clinical study of method for supplementting kidney, resolving phlegm and dredging collaterals in treatment of amenorrhea with phlegm-dampness. Zhong Yi Yao Xin Xi. 2000; ( 2):44-45. Chinese.
索玉平, 王力, 陈惠铮, 王秀霞 . 补肾化痰通络治疗痰湿型闭经的临床研究.中医药信息. 2000; ( 2):44-45.
[12] Hou LH, Ma LJ, Yu FJ , Wu LJ . Hormone monitor of integrated traditional Chinese and Western medicine therapy in treatment of 16 cases of polycystic ovary syndrome. Zhong Yi Yao Xue Bao. 2000; 28(1):48-49. Chinese.
侯丽辉, 马丽君, 于凤娟, 吴丽娟 . 性激素监测中西药治疗多囊卵巢综合征16例.中医药学报. 2000; 28(1):48-49.
[13] Xia Y. Cangfu Daotan Decoction in treatment of 30 cases of obese women with polycystic ovary syndrome. Tianjin Zhong Yi Yao. 2004; 21(2):169. Chinese.
doi: 10.3969/j.issn.1672-1519.2004.02.039
夏阳 . 苍附导痰汤加减治疗肥胖型多囊卵巢综合征30 例.天津中医药. 2004; 21(2):169.
doi: 10.3969/j.issn.1672-1519.2004.02.039
[14] Chen JL, Liu L . A therapy for resolving phlegm and supplementing kidney in treatmemt of 57 cases of obesity amenorrhea. Shanghai Zhong Yi Yao Za Zhi. 2004; 38(5):40-41. Chinese.
doi: 10.3969/j.issn.1007-1334.2004.05.018
陈锦黎, 刘敛 . 化痰补肾法治疗肥胖型闭经57例.上海中医药杂志. 2004; 38(5):40-41.
doi: 10.3969/j.issn.1007-1334.2004.05.018
[15] Zhang QP. Discussion of therapy for supplementing kidney and activating blood in treatment of polycystic ovary syndrome. Zhongguo Zhong Yi Yao Xin Xi Za Zhi. 2004; 11(11):1014-1015. Chinese.
章巧萍 . 浅谈补肾活血法治疗多囊卵巢综合征.中国中医药信息杂志. 2004; 11(11):1014-1015.
[16] Zhang F . Prescription for supplementing kidney, expelling stasis and resolving phlegm in treatment of 35 cases of polycystic ovary syndrome. Zhong Yi Yao Xue Kan. 2004; 22(2):336-337. Chinese.
doi: 10.3969/j.issn.1673-7717.2004.02.077
张帆 . 补肾化痰祛瘀方治疗多囊卵巢综合征35例.中医药学刊. 2004; 22(2):336-337.
doi: 10.3969/j.issn.1673-7717.2004.02.077
[17] Ni L, Gao H. Therapy for supplementing kidney, drying dampness and resolving phlegm in treatment of polycystic ovary syndrome. Zhong Yi Yao Xue Bao. 2002; 30(2):28-29. Chinese.
doi: 10.3969/j.issn.1002-2392.2002.02.020
倪玲, 髙红 . 补肾燥湿化痰治疗多囊卵巢综合征.中医药学报. 2002; 30(2):28-29.
doi: 10.3969/j.issn.1002-2392.2002.02.020
[18] He L, Guo S , Liu CY . Effect of nourishing qi therapy on insulin resistance and TNF-a concentration in fat tissues of diet-induced obese rats. Zhongguo Zhong Yi Yao Xin Xi Za Zhi. 2003; 10(2):32-33. Chinese with abstract in English.
doi: 10.3969/j.issn.1005-5304.2003.02.015
何丽, 郭盛, 刘昌玉 . 健脾益气法对营养性肥胖大鼠胰岛素敏感指数及脂肪组织中肿瘤坏死因子-a的影响. 中国中医药信息杂志. 2003; 10(2):32-33.
doi: 10.3969/j.issn.1005-5304.2003.02.015
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