健脾清化方治疗脾虚湿热型慢性肾衰的临床观察

doi:10.3736/jcim20050407

Abstract

Objective

To evaluate the effects of Jianpi Qinghua Recipe (JPQHR) on chronic renal failure with syndrome of dampness-heat due to spleen deficiency and its mechanism.

Methods

One hundred and six patients were randomly divided into two groups: control group (53 patients treated with routine therapy) and JPQHR-treated group (53 patients treated with routine therapy and JPQHR).

Results

Routine therapy combined with JPQHR could improve symptoms. The serum creatinine, blood urea nitrogen, triglyceride and low density lipoprotein decreased significantly in the JPQHR-treated group as compared with those in the control group (P<0.05), while the number of erythrocyte rosette-forming cells increased significantly in the JPQHR-treated group as compared with those in the control group (P<0.05).

Conclusion

Routine therapy combined with JPQHR can significantly decrease blood lipid level and strengthen cellular immune system, so it can lower the urine protein in the early and middle stages of chronic renal failure and improve renal function.

Key words: Jianpi Qinghua Recipe, Syndrome of dampness-heat due to spleen deficiency, Kidney failure, Chronic

CLC Number:

R692.5

Li-qun He, Gan Cai. Clinical study of chronic renal failure with syndrome of dampness-heat due to spleen deficiency treated with Jianpi Qinghua Recipe. Journal of Chinese Integrative Medicine, 2005, 3(4): 270-273.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20050407

http://www.jcimjournal.com/EN/Y2005/V3/I4/270

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References 14

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Group	n	SCr (μmol/L)	BUN (mmol/L)
JPQHR-treated group
Before treatment	53	236.98±115.22	11.52±5.06
After treatment	53	200.56±97.51*	10.51±4.73*
Control group
Before treatment	53	245.32±117.86	13.15±6.20
After treatment	53	243.44±122.63	13.00±5.87

Group	n	Ccr (ml/min)	Upr (g/24 h)
JPQHR-treated group
Before treatment	50	37.30±19.11	1.31±1.49
After treatment	50	40.34±18.47	1.12±1.22*
Control group
Before treatment	49	35.43±18.30	0.93±0.75
After treatment	49	33.91±18.80	0.85±0.76

Group	n	CH	TG	HDL	LDL
JPQHR-treated group
Before treatment	39	4.87±1.01	2.52±1.29	1.15±0.28	2.85±1.05
After treatment	39	4.58±1.04	1.81±1.32*^△	1.21±0.28^△△	2.17±0.93**^△△
Control group
Before treatment	39	4.44±0.75	2.04±0.92	1.14±0.29	2.04±0.92
After treatment	39	4.47±1.04	2.59±1.65	1.13±0.26	2.59±1.65

Group	n	EtRFC	IgG
JPQHR-treated group
Before treatment	35	74.85±10.79	12.25±3.39
After treatment	35	79.81±9.01*^△	11.77±3.31
Control group
Before treatment	35	73.22±9.64	11.99±2.93
After treatment	35	74.51±8.79	11.39±2.61

Clinical study of chronic renal failure with syndrome of dampness-heat due to spleen deficiency treated with Jianpi Qinghua Recipe

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